scholarly journals Pharmacological characterization of the novel nociceptin/orphanin FQ receptor ligand, ZP120: in vitro and in vivo studies in mice

2002 ◽  
Vol 137 (3) ◽  
pp. 369-374 ◽  
Author(s):  
Anna Rizzi ◽  
Daniela Rizzi ◽  
Giuliano Marzola ◽  
Domenico Regoli ◽  
Bjarne Due Larsen ◽  
...  
Keyword(s):  
In Vivo Studies ◽  
The Novel ◽  
Orphanin Fq ◽  
Pharmacological Characterization ◽  
Receptor Ligand

In vitro and in vivo pharmacological characterization of the nociceptin/orphanin FQ receptor ligand Ac-RYYRIK-ol

2006 ◽  
Vol 539 (1-2) ◽  
pp. 39-48 ◽  
Author(s):  
Özge Gündüz ◽  
Anna Rizzi ◽  
Anna Baldisserotto ◽  
Remo Guerrini ◽  
Barbara Spagnolo ◽  
...  
Keyword(s):  
Orphanin Fq ◽  
Pharmacological Characterization ◽  
Receptor Ligand

scholarly journals In vitro and in vivo pharmacological characterization of the novel UT receptor ligand [Pen5 ,D Trp7 ,Dab8 ]urotensin II(4-11) (UFP-803)

2006 ◽  
Vol 147 (1) ◽  
pp. 92-100 ◽  
Author(s):  
Valeria Camarda ◽  
Martina Spagnol ◽  
Wei Song ◽  
Raffaella Vergura ◽  
Adelheid L Roth ◽  
...  
Keyword(s):  
The Novel ◽  
Urotensin Ii ◽  
Pharmacological Characterization ◽  
Receptor Ligand

In vitro and in vivo pharmacological characterization of the novel NK1 receptor selective antagonist Netupitant

Peptides ◽  
2012 ◽  
Vol 37 (1) ◽  
pp. 86-97 ◽  
Author(s):  
Anna Rizzi ◽  
Barbara Campi ◽  
Valeria Camarda ◽  
Stefano Molinari ◽  
Sergio Cantoreggi ◽  
...  
Keyword(s):  
The Novel ◽  
Nk1 Receptor ◽  
Pharmacological Characterization ◽  
Selective Antagonist

Pharmacological characterization of naloxegol: in vitro and in vivo studies

2021 ◽  
pp. 174132
Author(s):  
Anna Costanzini ◽  
Chiara Ruzza ◽  
Joaquim Azevedo Neto ◽  
Chiara Sturaro ◽  
Davide Malfacini ◽  
...  
Keyword(s):  
In Vivo Studies ◽  
Pharmacological Characterization

In vitro and in vivo pharmacological characterization of the novel neuropeptide S receptor ligands QA1 and PI1

Peptides ◽  
2013 ◽  
Vol 48 ◽  
pp. 27-35 ◽  
Author(s):  
V. Camarda ◽  
C. Ruzza ◽  
A. Rizzi ◽  
C. Trapella ◽  
R. Guerrini ◽  
...  
Keyword(s):  
The Novel ◽  
Receptor Ligands ◽  
Neuropeptide S ◽  
Pharmacological Characterization

scholarly journals A NewIn VivoModel System to Assess the Toxicity of Semiconductor Nanocrystals

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Angela Tino ◽  
Alfredo Ambrosone ◽  
Lucia Mattera ◽  
Valentina Marchesano ◽  
Andrei Susha ◽  
...  
Keyword(s):  
Semiconductor Nanocrystals ◽  
Minimal Risk ◽  
The Novel ◽  
Toxicological Evaluation ◽  
Hydra Vulgaris ◽  
Population Growth Rates ◽  
Single Structure

In the emerging area of nanotechnology, a key issue is related to the potential impacts of the novel nanomaterials on the environment and human health, so that this technology can be used with minimal risk. Specifically designed to combine on a single structure multipurpose tags and properties, smart nanomaterials need a comprehensive characterization of both chemicophysical properties and adequate toxicological evaluation, which is a challenging endeavour; thein vitrotoxicity assays that are often employed for nanotoxicity assessments do not accurately predictin vivoresponse. To overcome these limitations and to evaluate toxicity characteristics of cadmium telluride quantum dots in relation to surface coatings, we have employed the freshwater polypHydra vulgarisas a model system. We assessedin vivoacute and sublethal toxicity by scoring for alteration of morphological traits, population growth rates, and influence on the regenerative capabilities providing new investigation clues for nanotoxicology purposes.

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