Functional Characterization of the Novel Neuronal Nicotinic Acetylcholine Receptor Ligand GTS-21 In Vitro and In Vivo

Functional Characterization ◽

The Novel ◽

Receptor Ligand ◽

In Vitro Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167072 ◽

2010 ◽

Vol 334 (3) ◽

pp. 863-874 ◽

Cited By ~ 40

Author(s):

John Malysz ◽

David J. Anderson ◽

Jens H. Grønlien ◽

Jianguo Ji ◽

William H. Bunnelle ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

In vitro and in vivo effects of an α3 neuronal nicotinic acetylcholine receptor antisense oligonucleotide

Molecular Brain Research ◽

10.1016/j.molbrainres.2004.06.019 ◽

2004 ◽

Vol 129 (1-2) ◽

pp. 67-79 ◽

Cited By ~ 4

Author(s):

Monique R. Adams ◽

Arthur L. Nikkel ◽

Diana L. Donnelly-Roberts ◽

Andrew T. Watt ◽

Joseph F. Johnston ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Antisense Oligonucleotide ◽

Nicotinic Acetylcholine ◽

In Vivo Effects

In Vivo Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167213 ◽

2010 ◽

Vol 334 (3) ◽

pp. 875-886 ◽

Cited By ~ 74

Author(s):

R. Scott Bitner ◽

William H. Bunnelle ◽

Michael W. Decker ◽

Karla U. Drescher ◽

Kathy L. Kohlhaas ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

In vitro pharmacological characterization of (±)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand

Brain Research ◽

10.1016/s0006-8993(03)02979-2 ◽

2003 ◽

Vol 981 (1-2) ◽

pp. 85-98 ◽

Cited By ~ 15

Author(s):

Tadimeti S. Rao ◽

Pamala B. Adams ◽

Lucia D. Correa ◽

Emily M. Santori ◽

Aida I. Sacaan ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Ligand ◽

A Novel Positive Allosteric Modulator of the 7 Neuronal Nicotinic Acetylcholine Receptor: In Vitro and In Vivo Characterization

Journal of Neuroscience ◽

10.1523/jneurosci.5269-04.2005 ◽

2005 ◽

Vol 25 (17) ◽

pp. 4396-4405 ◽

Cited By ~ 321

Author(s):

R. S. Hurst

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulator ◽

Positive Allosteric Modulator ◽

Nicotinic Acetylcholine ◽

In Vivo Characterization

Functional Characterization of AT-1001, an α3β4 Nicotinic Acetylcholine Receptor Ligand, at Human α3β4 and α4β2 nAChR

Nicotine & Tobacco Research ◽

10.1093/ntr/ntu170 ◽

2014 ◽

Vol 17 (3) ◽

pp. 361-367 ◽

Cited By ~ 11

Author(s):

Nurulain T. Zaveri ◽

Sonia Bertrand ◽

Dennis Yasuda ◽

Daniel Bertrand

Keyword(s):

Acetylcholine Receptor ◽

Functional Characterization ◽

Receptor Ligand ◽

Functional characterization of a mutated chicken α 7 nicotinic acetylcholine receptor subunit with a leucine residue inserted in transmembrane domain 2

British Journal of Pharmacology ◽

10.1038/sj.bjp.0701866 ◽

1998 ◽

Vol 124 (4) ◽

pp. 747-755 ◽

Cited By ~ 2

Author(s):

Steven D Buckingham ◽

Charlotte Adcock ◽

Mark S P Sansom ◽

David B Sattelle ◽

Howard A Baylis

Keyword(s):

Acetylcholine Receptor ◽

Transmembrane Domain ◽

Functional Characterization ◽

Receptor Subunit ◽

Nicotinic Acetylcholine ◽

Leucine Residue

P4-310: Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1755 ◽

2013 ◽

Vol 9 ◽

pp. P817-P818 ◽

Cited By ~ 5

Author(s):

Robert Bitner ◽

David Anderson ◽

Karla Drescher ◽

Kathy Kohlhaas ◽

Halvard Gronlien ◽

...

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Therapeutic Agent ◽

Nicotinic Acetylcholine ◽

Alpha 7 ◽

Novel Therapeutic

Pharmacological characterization of nicotinic acetylcholine receptor (nACh-R)-mediated acetylcholine release in rat brain - in vivo microdialysis study

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)44859-2 ◽

1997 ◽

Vol 73 ◽

pp. 88

Author(s):

Yoshihiro Tani ◽

Kyoshi Saito ◽

Masahiro Imoto ◽

Tomochika Ohno

Keyword(s):

Rat Brain ◽

Acetylcholine Receptor ◽

Acetylcholine Release ◽

In Vivo Microdialysis ◽

Nicotinic Acetylcholine ◽

Microdialysis Study

Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.07.021 ◽

2015 ◽

Vol 23 (17) ◽

pp. 5693-5701 ◽

Cited By ~ 1

Author(s):

Pauline W. Ondachi ◽

Zhuo Ye ◽

Ana H. Castro ◽

Charles W. Luetje ◽

M. Imad Damaj ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Binding ◽