scholarly journals Successful treatment of a patient with Klinefelter's syndrome complicated by mediastinal germ cell tumor and AML(M7)

2008 ◽  
Vol 41 (10) ◽  
pp. 907-908 ◽  
Author(s):  
H Hiramatsu ◽  
T Morishima ◽  
H Nakanishi ◽  
Y Mizushima ◽  
M Miyazaki ◽  
...  
1996 ◽  
Vol 43 (6) ◽  
pp. 1035
Author(s):  
Yong Jo Kim ◽  
Gyo Seon Kwun ◽  
Young Wo Lee ◽  
Kyung Tae Kim ◽  
Yeon Hee Park ◽  
...  

1987 ◽  
Vol 5 (8) ◽  
pp. 1290-1294 ◽  
Author(s):  
C R Nichols ◽  
N A Heerema ◽  
C Palmer ◽  
P J Loehrer ◽  
S D Williams ◽  
...  

Several case reports have suggested an association of primary mediastinal germ cell tumor (PMGCT) and Klinefelter's syndrome (KS). In an effort to confirm this association, 22 patients with mediastinal germ cell tumors had chromosome studies performed in a prospective fashion. Five patients (22%) had karyotypic or pathologic evidence of KS. All of the patients with KS had germ cell tumors of the nonseminomatous subtype and were relatively young (median age, 15 years). The literature confirms the findings of a young median age (18 years), nonseminomatous subtype, and mediastinal location of the germ cell neoplasm. We conclude that patients with KS are predisposed to the development of mediastinal nonseminomatous germ cell cancers.


2001 ◽  
Vol 15 (1) ◽  
pp. 28-32
Author(s):  
Arifumi Iwamaru ◽  
Takahiko Oyama ◽  
Ikuo Kamiyama ◽  
Taichiro Goto ◽  
Manabu Yamamoto ◽  
...  

1996 ◽  
Vol 57 (12) ◽  
pp. 2968-2973
Author(s):  
Yasufumi HAYASHI ◽  
Michihiko TAJIRI ◽  
Tatsushi YAMAGATA ◽  
Haruhiko ISHII ◽  
Kazuhiro SAKAMOTO ◽  
...  

1999 ◽  
Vol 6 (3) ◽  
pp. 158-161 ◽  
Author(s):  
KAZUNORI NAMIKI ◽  
AKIRA TSUCHIYA ◽  
KENJIRO NODA ◽  
HIRONORI OYAMA ◽  
KEIICHIRO ISHIBASHI ◽  
...  

2005 ◽  
Vol 12 (8) ◽  
pp. 765-767
Author(s):  
HIROMU INAI ◽  
KOJI KAWAI ◽  
YUKIO MORISHITA ◽  
MICHIO NAGATA ◽  
MASAYUKI NOGUCHI ◽  
...  

1983 ◽  
Vol 58 (1) ◽  
pp. 136-138 ◽  
Author(s):  
Asamitsu Ahagon ◽  
Yasuaki Yoshida ◽  
Koji Kusuno ◽  
Toshiro Uno

✓ A case is presented of suprasellar germinoma in a 20-year-old man with Klinefelter's syndrome. Hypogonadism is known to be a characteristic of Klinefelter's syndrome, and has often been described in cases of suprasellar germinoma. Thus, both pathological entities may mimic one another. It is emphasized that a chromosomal karyotype should be determined in every case of intracranial germ-cell tumor associated with hypogonadism.


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