CHAPTER 13. Mechanism of Action of a GluN2C- and GluN2D-Selective NMDA Receptor Positive Allosteric Modulator

Structural Determinants and Mechanism of Action of a GluN2C-selective NMDA Receptor Positive Allosteric Modulator

Molecular Pharmacology ◽

10.1124/mol.114.094516 ◽

2014 ◽

Vol 86 (5) ◽

pp. 548-560 ◽

Cited By ~ 42

Author(s):

Alpa Khatri ◽

Pieter B. Burger ◽

Sharon A. Swanger ◽

Kasper B. Hansen ◽

Sommer Zimmerman ◽

...

Keyword(s):

Nmda Receptor ◽

Mechanism Of Action ◽

Allosteric Modulator ◽

Structural Determinants

Faculty Opinions recommendation of An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726061211.793515244 ◽

2016 ◽

Author(s):

Leslie Iversen

Keyword(s):

Nmda Receptor ◽

Genetic Model ◽

Allosteric Modulator ◽

A novel NMDA receptor positive allosteric modulator that acts via the transmembrane domain

Neuropharmacology ◽

10.1016/j.neuropharm.2017.04.041 ◽

2017 ◽

Vol 121 ◽

pp. 204-218 ◽

Cited By ~ 15

Author(s):

Tzu-Ming Wang ◽

Brandon M. Brown ◽

Lunbin Deng ◽

Benjamin D. Sellers ◽

Patrick J. Lupardus ◽

...

Keyword(s):

Nmda Receptor ◽

Transmembrane Domain ◽

Allosteric Modulator ◽

The mGlu5 positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat

Neuropharmacology ◽

10.1016/j.neuropharm.2012.07.039 ◽

2013 ◽

Vol 64 ◽

pp. 240-247 ◽

Cited By ~ 25

Author(s):

Francois Gastambide ◽

Gary Gilmour ◽

Trevor W. Robbins ◽

Mark D. Tricklebank

Keyword(s):

Nmda Receptor ◽

Allosteric Modulator ◽

Nmda Receptor Antagonists ◽

Cognitive Effects ◽

Receptor Antagonists

Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors

Biochemical Pharmacology ◽

10.1016/j.bcp.2016.04.004 ◽

2016 ◽

Vol 110-111 ◽

pp. 92-108 ◽

Cited By ~ 5

Author(s):

Agnes Gasiorek ◽

Sarah M. Trattnig ◽

Philip K. Ahring ◽

Uffe Kristiansen ◽

Bente Frølund ◽

...

Keyword(s):

Functional Properties ◽

Mechanism Of Action ◽

Allosteric Modulator ◽

Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator

European Journal of Pharmacology ◽

10.1016/j.ejphar.2010.02.057 ◽

2010 ◽

Vol 639 (1-3) ◽

pp. 40-46 ◽

Cited By ~ 45

Author(s):

Holger Rosenbrock ◽

Gert Kramer ◽

Scott Hobson ◽

Eliza Koros ◽

Marc Grundl ◽

...

Keyword(s):

Nmda Receptor ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Allosteric Modulator ◽

Functional Interaction ◽

Metabotropic Glutamate Receptor 5 ◽

Metabotropic Glutamate

Delineation of the functional properties and the mechanism of action of AA29504, an allosteric agonist and positive allosteric modulator of GABA A receptors

Biochemical Pharmacology ◽

10.1016/j.bcp.2018.02.015 ◽

2018 ◽

Vol 150 ◽

pp. 305-319 ◽

Cited By ~ 3

Author(s):

Emma Rie Olander ◽

Nawid Madjroh ◽

Lennart Bunch ◽

Pella Cecilia Söderhielm ◽

Anders A. Jensen

Keyword(s):

Functional Properties ◽

Mechanism Of Action ◽

Allosteric Modulator ◽

Gaba A

Functional properties and mechanism of action of PPTQ, an allosteric agonist and low nanomolar positive allosteric modulator at GABAA receptors

Biochemical Pharmacology ◽

10.1016/j.bcp.2017.11.006 ◽

2018 ◽

Vol 147 ◽

pp. 153-169 ◽

Cited By ~ 2

Author(s):

Nawid Madjroh ◽

Emma Rie Olander ◽

Christoffer Bundgaard ◽

Pella Cecilia Söderhielm ◽

Anders A. Jensen

Keyword(s):

Functional Properties ◽

Mechanism Of Action ◽

Gabaa Receptors ◽

Allosteric Modulator ◽

Faculty Opinions recommendation of An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726061211.793514695 ◽

2016 ◽

Author(s):

Celeste Napier

Keyword(s):

Nmda Receptor ◽

Genetic Model ◽

Allosteric Modulator ◽

Unravelling the mechanism of action of NS9283, a positive allosteric modulator of (α4)3(β2)2nicotinic ACh receptors

British Journal of Pharmacology ◽

10.1111/bph.12095 ◽

2013 ◽

Vol 168 (8) ◽

pp. 2000-2010 ◽

Cited By ~ 18

Author(s):

M Grupe ◽

AA Jensen ◽

PK Ahring ◽

JK Christensen ◽

M Grunnet

Keyword(s):

Mechanism Of Action ◽

Allosteric Modulator ◽

Ach Receptors