CHAPTER 2. Respiratory Syncytial Virus Fusion Inhibitors

2013 ◽  
pp. 29-62 ◽  
Author(s):  
David Sperandio ◽  
Richard Mackman
Keyword(s):  
Respiratory Syncytial Virus ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Syncytial Virus

scholarly journals Discovery of (aza)indole derivatives as novel respiratory syncytial virus fusion inhibitors

MedChemComm ◽  
2019 ◽  
Vol 10 (6) ◽  
pp. 970-973
Author(s):  
Xiufang Zheng ◽  
Chungen Liang ◽  
Lisha Wang ◽  
Kun Miao ◽  
Baoxia Wang ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Indole Derivatives ◽  
New Class ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Syncytial Virus

A new class of (aza)indole derivatives have been identified as potent RSV fusion inhibitors.

scholarly journals Discovery of Piperazinylquinoline Derivatives as Novel Respiratory Syncytial Virus Fusion Inhibitors

2016 ◽  
Vol 7 (6) ◽  
pp. 558-562 ◽  
Author(s):  
Xiufang Zheng ◽  
Lisha Wang ◽  
Baoxia Wang ◽  
Kun Miao ◽  
Kunlun Xiang ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Syncytial Virus

Respiratory syncytial virus fusion inhibitors. Part 3: Water-soluble benzimidazol-2-one derivatives with antiviral activity in vivo

2006 ◽  
Vol 16 (5) ◽  
pp. 1115-1122 ◽  
Author(s):  
Kuo-Long Yu ◽  
Xiangdong Alan Wang ◽  
Rita L. Civiello ◽  
Ashok K. Trehan ◽  
Bradley C. Pearce ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Antiviral Activity ◽  
Water Soluble ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Syncytial Virus

Discovery of Benzoazepinequinoline (BAQ) Derivatives as Novel, Potent, Orally Bioavailable Respiratory Syncytial Virus Fusion Inhibitors

2018 ◽  
Vol 61 (22) ◽  
pp. 10228-10241 ◽  
Author(s):  
Xiufang Zheng ◽  
Chungen Liang ◽  
Lisha Wang ◽  
Baoxia Wang ◽  
Yongfu Liu ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Orally Bioavailable ◽  
Syncytial Virus

scholarly journals Molecular mechanism of respiratory syncytial virus fusion inhibitors

2015 ◽  
Vol 12 (2) ◽  
pp. 87-93 ◽  
Author(s):  
Michael B Battles ◽  
Johannes P Langedijk ◽  
Polina Furmanova-Hollenstein ◽  
Supranee Chaiwatpongsakorn ◽  
Heather M Costello ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Molecular Mechanism ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Syncytial Virus

scholarly journals Discovery of Imidazopyridine Derivatives as Highly Potent Respiratory Syncytial Virus Fusion Inhibitors

2015 ◽  
Vol 6 (3) ◽  
pp. 359-362 ◽  
Author(s):  
Song Feng ◽  
Di Hong ◽  
Baoxia Wang ◽  
Xiufang Zheng ◽  
Kun Miao ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Imidazopyridine Derivatives ◽  
Syncytial Virus

Respiratory syncytial virus fusion inhibitors. Part 4: Optimization for oral bioavailability

2007 ◽  
Vol 17 (4) ◽  
pp. 895-901 ◽  
Author(s):  
Kuo-Long Yu ◽  
Ny Sin ◽  
Rita L. Civiello ◽  
X. Alan Wang ◽  
Keith D. Combrink ◽  
...  
Keyword(s):  
Respiratory Syncytial Virus ◽  
Oral Bioavailability ◽  
Fusion Inhibitors ◽  
Virus Fusion ◽  
Syncytial Virus
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