Single molecule level detection of allophycocyanin by surface enhanced resonance Raman scattering

The Analyst ◽  
2007 ◽  
Vol 132 (7) ◽  
pp. 633 ◽  
Author(s):  
Colin D. McGuinness ◽  
Alexander M. Macmillan ◽  
Jan Karolin ◽  
W. Ewen Smith ◽  
Duncan Graham ◽  
...  
2001 ◽  
Vol 105 (15) ◽  
pp. 3673-3679 ◽  
Author(s):  
C. Eggeling ◽  
J. Schaffer ◽  
C. A. M. Seidel ◽  
J. Korte ◽  
G. Brehm ◽  
...  

2005 ◽  
Vol 45 (supplement) ◽  
pp. S197
Author(s):  
K. Watanabe ◽  
M. Tsunoda ◽  
T. Ueno ◽  
M. Yamagishi ◽  
T. Funatsu

2001 ◽  
Vol 73 (15) ◽  
pp. 3674-3678 ◽  
Author(s):  
Carlos J. L. Constantino ◽  
Tibebe Lemma ◽  
Patricia A. Antunes ◽  
Ricardo Aroca

Nanoscale ◽  
2016 ◽  
Vol 8 (6) ◽  
pp. 3337-3349 ◽  
Author(s):  
Sylwester Gawinkowski ◽  
Maria Pszona ◽  
Alexandr Gorski ◽  
Joanna Niedziółka-Jönsson ◽  
Izabela Kamińska ◽  
...  

Single molecule surface-enhanced resonance Raman scattering (SERRS) spectra have been obtained for the parent porphycene (Pc-d0) and its deuterated isotopologue (Pc-d12), located on gold and silver nanoparticles.


1995 ◽  
Vol 49 (6) ◽  
pp. 780-784 ◽  
Author(s):  
Katrin Kneipp ◽  
Yang Wang ◽  
Ramachandra R. Dasari ◽  
Michael S. Feld

We have measured surface-enhanced resonance Raman scattering (SERRS) spectra of rhodamine 6G (R6G) at concentrations as low as 8 × 10−16 M in colloidal silver solution activated by NaCl ions. The spectra were measured with a fiber-optic probe using the 514.5-nm argon-ion laser line as excitation source and a charge-coupled-device (CCD) detection system. The correlation of SERRS photo counts and R6G concentration was found to be linear between 8 × 10−11 and 8 × 10−14 M concentrations within our experimental accuracy. Experiments conducted with small scattering volumes show that fewer than 100 R6G molecules are sufficient to give rise to a SERRS spectrum with reasonable signal-to-noise ratio. These results demonstrate that in certain cases SERRS can achieve detection limits comparable to those for fluorescence spectroscopy, and at the same time provides higher structural specificity than fluorescence. The possibilities of using SERRS for single molecule detection are discussed.


Sign in / Sign up

Export Citation Format

Share Document