Organocatalytic dynamic kinetic resolution via conjugate addition: synthesis of chiral trans-2,5-dialkylcyclohexanones

2012 ◽  
Vol 10 (41) ◽  
pp. 8260 ◽  
Author(s):  
Ganesh Pandey ◽  
Priyanka A. Adate ◽  
Vedavati G. Puranik
Keyword(s):  
Kinetic Resolution ◽  
Conjugate Addition ◽  
Dynamic Kinetic Resolution

scholarly journals Racemic hemiacetals as oxygen-centered pronucleophiles triggering cascade 1,4-addition/Michael reaction through dynamic kinetic resolution under iminium catalysis. Development and mechanistic insights

2017 ◽  
Vol 8 (4) ◽  
pp. 2904-2913 ◽  
Author(s):  
Ane Orue ◽  
Uxue Uria ◽  
David Roca-López ◽  
Ignacio Delso ◽  
Efraím Reyes ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Michael Reaction ◽  
Conjugate Addition ◽  
Cascade Process ◽  
Dynamic Kinetic Resolution ◽  
Single Stereoisomer

Racemic 2-hydroxydihydropyran-5-ones react as unconventional O-pronucleophiles in a conjugate addition/Michael reaction cascade process under DKR, leading to the formation of a single stereoisomer out of 16 possible ones.

Racemization of Amines and Related Derivatives Leading to Their Dynamic Kinetic Resolution

2013 ◽  
Vol 17 (11) ◽  
pp. 1225-1234 ◽  
Author(s):  
Cheng-jun Jiang ◽  
Gui-lin Cheng
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Dynamic Kinetic Resolution of Carboxylic Esters Catalyzed by Chiral PPY N-Oxides: Synthesis of Nonsteroidal Anti-Inflammatory Drugs and Mechanistic Insights

ACS Catalysis ◽  
2021 ◽  
pp. 8183-8196
Author(s):  
Ming-Sheng Xie ◽  
Ning Li ◽  
Yin Tian ◽  
Xiao-Xia Wu ◽  
Yun Deng ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Carboxylic Esters

Development of a Robust and Highly Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

2020 ◽  
Vol 24 (6) ◽  
pp. 1164-1174
Author(s):  
Austin G. Smith ◽  
Matthew M. Bio ◽  
John T. Colyer ◽  
Khalid Diker ◽  
Gilles Gorins ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides

2021 ◽  
Author(s):  
Linghui Qian ◽  
Ling-Fei Tao ◽  
Wen-Tao Wang ◽  
Ehtesham Jameel ◽  
Zhang-Hong Luo ◽  
...  
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

Stereoselective Synthesis of b‐Branched Aromatic a‐Amino Acids via Biocatalytic Dynamic Kinetic Resolution

2021 ◽  
Author(s):  
Fuzhuo Li ◽  
Li-Cheng Yang ◽  
Jingyang Zhang ◽  
Jason Chen ◽  
Hans Renata
Keyword(s):  
Amino Acids ◽  
Kinetic Resolution ◽  
Stereoselective Synthesis ◽  
Dynamic Kinetic Resolution

Efforts towards a Noyori reduction of a 3-fluorpiperidin-4-one with dynamic kinetic resolution

2021 ◽  
pp. 152764
Author(s):  
Jacques Le Paih ◽  
Dane A. Goff ◽  
Rajinder Singh ◽  
Simon J. Shaw
Keyword(s):  
Kinetic Resolution ◽  
Dynamic Kinetic Resolution

An Efficient Dynamic Kinetic Resolution of N-Heterocyclic 1,2-Amino Alcohols

2011 ◽  
Vol 353 (13) ◽  
pp. 2321-2327 ◽  
Author(s):  
Richard Lihammar ◽  
Renaud Millet ◽  
Jan-E. Bäckvall
Keyword(s):  
Kinetic Resolution ◽  
Amino Alcohols ◽  
Dynamic Kinetic Resolution
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