scholarly journals Development of a general methodology for labelling peptide–morpholino oligonucleotide conjugates using alkyne–azide click chemistry

2013 ◽  
Vol 49 (87) ◽  
pp. 10260-10262 ◽  
Author(s):  
Fazel Shabanpoor ◽  
Michael J. Gait
Keyword(s):  
Click Chemistry ◽  
Morpholino Oligonucleotide ◽  
General Methodology ◽  
Oligonucleotide Conjugates

Synthesis of Mannose and Galactose Oligonucleotide Conjugates by Bi-click chemistry

2009 ◽  
Vol 74 (3) ◽  
pp. 1218-1222 ◽  
Author(s):  
Gwladys Pourceau ◽  
Albert Meyer ◽  
Jean-Jacques Vasseur ◽  
François Morvan
Keyword(s):  
Click Chemistry ◽  
Oligonucleotide Conjugates

Perylene Diimide–Oligonucleotide Conjugates Constructed by Click Chemistry

2007 ◽  
Vol 26 (6-7) ◽  
pp. 751-754 ◽  
Author(s):  
Alexey V. Ustinov ◽  
Veronika V. Dubnyakova ◽  
Vladimir A. Korshun
Keyword(s):  
Click Chemistry ◽  
Perylene Diimide ◽  
Oligonucleotide Conjugates

scholarly journals Oligo switches: photoresponsive oligonucleotide conjugates by solid-supported click chemistry

RSC Advances ◽  
2013 ◽  
Vol 3 (6) ◽  
pp. 1652-1655 ◽  
Author(s):  
Colin Freeman ◽  
Joseph S. Vyle ◽  
Frances Heaney
Keyword(s):  
Click Chemistry ◽  
Oligonucleotide Conjugates

Oligonucleotide Conjugates by Means of Copper-Free Click Chemistry - Expanding the Repertoire of Strained Cyclooctyne Phosphoramidites

Synthesis ◽  
2011 ◽  
Vol 2011 (17) ◽  
pp. 2724-2732 ◽  
Author(s):  
Gijsbert van der Marel ◽  
Dmitri Filippov ◽  
Pieter van Delft ◽  
Evert van Schie ◽  
Nico Meeuwenoord ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Oligonucleotide Conjugates

A convenient ‘click chemistry’ approach to perylene diimide–oligonucleotide conjugates

Tetrahedron ◽  
2008 ◽  
Vol 64 (7) ◽  
pp. 1467-1473 ◽  
Author(s):  
Alexey V. Ustinov ◽  
Veronika V. Dubnyakova ◽  
Vladimir A. Korshun
Keyword(s):  
Click Chemistry ◽  
Perylene Diimide ◽  
Oligonucleotide Conjugates

General Methodology for Evaluating Composite Action in Insulated Wall Panels

2017 ◽  
Author(s):  
Jaiden Olsen ◽  
Salam Al-Rubaye ◽  
Taylor Sorensen ◽  
Marc Maguire
Keyword(s):  
Composite Action ◽  
General Methodology ◽  
Wall Panels

PLC Based Sub-Assembly Station with Automated Guided Vehicle

2018 ◽  
Vol 6 (7) ◽  
pp. 256
Author(s):  
K. S. Margaret ◽  
G. Sathish Kumar ◽  
J. Narendiran ◽  
M. Raman
Keyword(s):  
Sequential Procedure ◽  
Automated Guided Vehicle ◽  
Work Station ◽  
General Methodology ◽  
Automatic Guided Vehicle ◽  
Store Room ◽  
Destination Point ◽  
Storage Bins

The aim of the project is to build an assembly station with the preventive section under the process of poke yoke system. Poke yoke is the general methodology following in industry to avoid mismatching product in assembly stations.  The main aim of this project is to avoid assembling process when the sequential procedure is not followed. The project also deals with AGV – Automatic Guided Vehicle. It automatically shifts the assembling components from store room to work station when the count of components decreases in storage bin. When the material count in the storage bins reaches the preset count it will pass signal to store room, the components will be filled manually in AGV storage bins and then the AGV is moved to the destination point (work station).

Click Chemistry Expedited Radiosynthesis: Sulfur [18F]fluoride Exchange of Aryl Fluorosulfates

2019 ◽  
Author(s):  
Qinheng Zheng ◽  
Hongtao Xu ◽  
Hua Wang ◽  
Wen-Ge Han Du ◽  
Nan Wang ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Performance ◽  
Isotopic Exchange ◽  
Tumor Imaging ◽  
Radiochemical Yield ◽  
Exchange Method ◽  
Molar Activity ◽  
Positron Emission ◽  
Sulfur Fluoride

The lack of simple, efficient [<sup>18</sup>F]fluorination processes and new target-specific organofluorine probes remains the major challenge of fluorine-18-based positron emission tomography (PET). We report here a fast isotopic exchange method for the radiosynthesis of aryl [<sup>18</sup>F]fluorosulfate based PET agents enabled by the emerging sulfur fluoride exchange (SuFEx) click chemistry. The method has been applied to the fully-automated <sup>18</sup>F-radiolabeling of twenty-five structurally diverse aryl fluorosulfates with excellent radiochemical yield (83–100%) and high molar activity (up to 281 GBq µmol<sup>–1</sup>) at room temperature in 30 seconds. The purification of radiotracers requires no time-consuming high-performance liquid chromatography (HPLC), but rather a simple cartridge filtration. The utility of aryl [<sup>18</sup>F]fluorosulfate is demonstrated by the <i>in vivo</i> tumor imaging by targeting poly(ADP-ribose) polymerase 1 (PARP1).

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