Novel 99mTc radiolabeled folate complexes with PEG linkers for FR-positive tumor imaging: synthesis and biological evaluation

RSC Advances ◽  
2014 ◽  
Vol 4 (61) ◽  
pp. 32197-32206 ◽  
Author(s):  
Fang Xie ◽  
Chun Zhang ◽  
Qian Yu ◽  
Yan Pang ◽  
Yuan Chen ◽  
...  
Keyword(s):  
Tumor Imaging ◽  
Folate Receptor ◽  
Biological Evaluation ◽  
Imaging Agent ◽  
The Novel ◽  
Novel Complex ◽  
Synthesis And Biological Evaluation ◽  
Tumor Imaging Agent

The novel complex 99mTc(FA-PEG2-HYNIC)(tricine/TPPTS) was clearly visualized at 120 min p.i. at the FR-positive tumor, highlighting its potential as an effective folate receptor tumor imaging agent.

Synthesis and biological evaluation of 99mTc(CO)3(His–CB) as a tumor imaging agent

2012 ◽  
Vol 22 (24) ◽  
pp. 7406-7409 ◽  
Author(s):  
Jianjun Wang ◽  
Jing Yang ◽  
Xiaojiang Duan ◽  
Yanhua Zhang ◽  
Wenjiang Yang ◽  
...  
Keyword(s):  
Tumor Imaging ◽  
Biological Evaluation ◽  
Imaging Agent ◽  
Synthesis And Biological Evaluation ◽  
Tumor Imaging Agent

Synthesis and preliminary biological evaluation of a99mTc-chlorambucil derivative as a potential tumor imaging agent

2016 ◽  
Vol 60 (2) ◽  
pp. 116-123 ◽  
Author(s):  
Jianguo Lin ◽  
Ling Qiu ◽  
Gaochao Lv ◽  
Ke Li ◽  
Wei Wang ◽  
...  
Keyword(s):  
Tumor Imaging ◽  
Biological Evaluation ◽  
Imaging Agent ◽  
Tumor Imaging Agent
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