Enantioselective total synthesis of the highly selective sphingosine-1-receptor VPC01091 by the Heck desymmetrization of a non-activated cyclopentene-fused spiro-pyrrolidinone
2016 ◽
Vol 14
(40)
◽
pp. 9476-9480
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The total synthesis of VPC01091 was accomplished in a concise manner, in a good overall yield of 40% from ethyl nitroacetate and 94% ee.
2002 ◽
Vol 43
(3)
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pp. 493-497
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2015 ◽
Vol 80
(17)
◽
pp. 8859-8867
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1997 ◽
Vol 38
(25)
◽
pp. 4473-4476
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