Asymmetric synthesis of CF3- and indole-containing tetrahydro-β-carbolines via chiral spirocyclic phosphoric acid-catalyzed aza-Friedel–Crafts reaction
Keyword(s):
An enantioselective aza-Friedel–Crafts reaction of indoles with 1-trifluoromethyl-3,4-dihydro-β-carbolines has been developed to afford tetrahydro-β-carbolines with a CF3- and indole-containing quaternary stereocenter by using chiral phosphoric acid catalysis.
2019 ◽
Vol 60
(18)
◽
pp. 1262-1264
◽
2020 ◽
Vol 59
(6)
◽
pp. 2333-2337
◽
Keyword(s):
2017 ◽
Vol 83
(1)
◽
pp. 364-373
◽
Keyword(s):
2018 ◽
Vol 57
(34)
◽
pp. 11004-11008
◽
Keyword(s):