Mild dynamic kinetic resolution of amines by coupled visible-light photoredox and enzyme catalysis

A mild and efficient dynamic kinetic resolution (DKR) of amines was achieved by combining visible-light-induced photoredox catalysis and enzyme catalysis. This dual catalytic system was appropriate for both monoamines and 1,4-diamines.

Download Full-text

Dynamic Kinetic Resolution of Secondary Diols via Coupled Ruthenium and Enzyme Catalysis

The Journal of Organic Chemistry ◽

10.1021/jo990447u ◽

1999 ◽

Vol 64 (14) ◽

pp. 5237-5240 ◽

Cited By ~ 76

Author(s):

B. Anders Persson ◽

Fernando F. Huerta ◽

Jan-E. Bäckvall

Keyword(s):

Enzyme Catalysis ◽

Kinetic Resolution ◽

Dynamic Kinetic Resolution

Download Full-text

Combining Oxoammonium Cation Mediated Oxidation and Photoredox Catalysis for the Conversion of Aldehydes into Nitriles

Synlett ◽

10.1055/s-0037-1610272 ◽

2018 ◽

Vol 29 (16) ◽

pp. 2185-2190 ◽

Cited By ~ 5

Author(s):

Nicholas Leadbeater ◽

Jyoti Nandi ◽

Mason Witko

Keyword(s):

Visible Light ◽

Nitrogen Source ◽

Catalytic System ◽

Aromatic Aldehydes ◽

Ammonium Persulfate ◽

Photoredox Catalysis ◽

Mediated Oxidation

A method to oxidize aromatic aldehydes to nitriles has been developed. It involves a dual catalytic system of 4-acetamido-TEMPO and visible-light photoredox catalysis. The reaction is performed using ammonium persulfate as both the terminal oxidant and nitrogen source.

Download Full-text

ChemInform Abstract: Dynamic Kinetic Resolution of Secondary Diols via Coupled Ruthenium and Enzyme Catalysis.

ChemInform ◽

10.1002/chin.199951031 ◽

2010 ◽

Vol 30 (51) ◽

pp. no-no

Author(s):

B. Anders Persson ◽

Fernando F. Huerta ◽

Jan-E. Baeckvall

Keyword(s):

Enzyme Catalysis ◽

Kinetic Resolution ◽

Dynamic Kinetic Resolution

Download Full-text

Regioselective C3-H Trifluoromethylation of 2H-Indazole Under Transition-Metal-Free Photoredox Catalysis

10.26434/chemrxiv.7796603.v1 ◽

2019 ◽

Cited By ~ 1

Author(s):

Arumugavel Murugan ◽

Venkata Nagarjuna Babu ◽

Nagaraj Sabarinathan ◽

Sharada Duddu. S

Keyword(s):

Transition Metal ◽

Visible Light ◽

Practical Approach ◽

Hypervalent Iodine ◽

Radical Mechanism ◽

Photoredox Catalysis ◽

Metal Free

Here we report a visible-light-promoted metal-free regioselective C3-H trifluoromehtylation reaction that proceeds via radical mechanism and which supported by control experiments. The combination of photoredox catalysis and hypervalent iodine reagent provides a practical approach for the present trifluoromethylation reaction and synthesis of a library of trifluoromethylated indazoles.

Download Full-text