scholarly journals A3- and A2B-nitrocorroles: synthesis and antiviral activity evaluation against human cytomegalovirus infection

2020 ◽  
Vol 11 (7) ◽  
pp. 771-782 ◽  
Author(s):  
Léo Bucher ◽  
Sandrine Kappler-Gratias ◽  
Nicolas Desbois ◽  
Kerstin Bystricky ◽  
Franck Gallardo ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Human Cytomegalovirus ◽  
Cytomegalovirus Infection ◽  
Selectivity Index ◽  
2Nd Generation ◽  
Activity Evaluation ◽  
Human Cytomegalovirus Infection

We report the 2nd generation of seventeen A2B- and A3-substituted fluoronitrocorroles and the discovery of optimized compounds with a selectivity index of >200 against hCMV.

Synthesis and Antiviral Activity Evaluation of Nitroporphyrins and Nitrocorroles as Potential Agents against Human Cytomegalovirus Infection

2015 ◽  
Vol 1 (8) ◽  
pp. 350-356 ◽  
Author(s):  
Claude P. Gros ◽  
Nicolas Desbois ◽  
Clément Michelin ◽  
Eloise Demilly ◽  
Anne-Françoise Tilkin-Mariamé ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Human Cytomegalovirus ◽  
Cytomegalovirus Infection ◽  
Activity Evaluation ◽  
Human Cytomegalovirus Infection

scholarly journals A3- and A2B-fluorocorroles: synthesis, X-ray characterization and antiviral activity evaluation against human cytomegalovirus infection

2020 ◽  
Vol 11 (7) ◽  
pp. 783-801
Author(s):  
Sandrine Kappler-Gratias ◽  
Léo Bucher ◽  
Nicolas Desbois ◽  
Yoann Rousselin ◽  
Kerstin Bystricky ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Human Cytomegalovirus ◽  
Cytomegalovirus Infection ◽  
Maximum Activity ◽  
X Ray ◽  
Activity Evaluation ◽  
Human Cytomegalovirus Infection ◽  
New Generation

New generation of anti hCMV molecules: 29 fluorinated corroles were studied for their antiviral activity evaluation against human cytomegalovirus infection and maximum activity is achieved for A2B-corroles with SI above 400.

scholarly journals SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity

2020 ◽  
Vol 16 (9) ◽  
pp. e1008855
Author(s):  
Simone De Meo ◽  
Valentina Dell’Oste ◽  
Rosa Molfetta ◽  
Valentina Tassinari ◽  
Lavinia Vittoria Lotti ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Human Cytomegalovirus ◽  
Cytomegalovirus Infection ◽  
Human Cytomegalovirus Infection
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