Synthesis of 2-hydroxytetrahydrofurans by Wacker-type oxidation of 1,1-disubstituted alkenes
1,1-Disubstituted alkenes feature high steric hindrance, which renders their Wacker-type oxidation difficult. We demonstrated the stereoselective synthesis of 2-hydroxytetrahydrofurans via the Wacker-type oxidation of 3-methyl-3-buten-1-ols by using a PdCl2(MeCN)2/NO/BQ catalyst...
1995 ◽
Keyword(s):
1996 ◽
Vol 24
(4)
◽
pp. 777-781
◽
Keyword(s):
Keyword(s):