Benzocaine-lipid membrane interaction and its application in the development of long-acting, encapsulated, local anesthetic formulations

2000 ◽  
Vol 28 (5) ◽  
pp. A203-A203
Author(s):  
L. M. A. Pinto ◽  
P. S. Melo ◽  
M. Haun ◽  
E. de Paula
Keyword(s):  
Local Anesthetic ◽  
Lipid Membrane ◽  
Membrane Interaction ◽  
Long Acting

scholarly journals Comparison of the Effect of Lidocaine versus a Lidocaine-Bupivacaine Combination in a Periprostatic Nerve Block Undergoing Transrectal Ultrasound-Guided Prostate Biopsy: A Double-Blind Randomized Controlled Trial

2015 ◽  
Vol 9 (3) ◽  
pp. 153-158 ◽  
Author(s):  
Ali H. Yilmaz ◽  
Elif Ziypak ◽  
Tevfik Ziypak ◽  
Mehmet Aksoy ◽  
Senol Adanur ◽  
...  
Keyword(s):  
Nerve Block ◽  
Local Anesthetic ◽  
Pain Control ◽  
Controlled Trial ◽  
Late Phase ◽  
Patient Comfort ◽  
Double Blind ◽  
Vas Scores ◽  
Long Acting ◽  
Periprostatic Nerve Block

Introduction: To determine whether a combination of the long acting local anesthetic, bupivacaine, and lidocaine is better than lidocaine alone in the long-term pain control, which is a short-acting anesthetic. Materials and Methods: In group 1, periprostatic nerve block was applied to both neurovascular areas with 2% lidocaine (5 ml) in an isotonic solution (5 ml). In group 2, the combination of 2% lidocaine (5 ml) and 5mg/ml bupivacaine (5 ml) was used for the PPNB. Results: In the first 30 minutes the mean VAS scores of groups 1 and 2 were 2.1 ± 0.2 and 1.2 ± 0.1, respectively (p = 0.002). VAS scores of group II determined at 1, 2, 4, 6, and 8 hours after the biopsy were significantly lower since it was (p < 0.05). Conclusion: While periprostatic nerve block for late phase pain control, applying a combination of a long-acting local anesthetic, such as bupivacaine, is effective in terms of pain control and patient comfort.

Long acting local anesthetic–polymer formulation to prolong the effect of analgesia

2007 ◽  
Vol 117 (1) ◽  
pp. 97-103 ◽  
Author(s):  
Ariella Shikanov ◽  
Abraham J. Domb ◽  
Carolyn F. Weiniger
Keyword(s):  
Local Anesthetic ◽  
Long Acting

scholarly journals Local anesthetic-membrane interaction: a multiequilibrium model.

1983 ◽  
Vol 80 (17) ◽  
pp. 5297-5301 ◽  
Author(s):  
H. H. Wang ◽  
J. Earnest ◽  
H. P. Limbacher
Keyword(s):  
Local Anesthetic ◽  
Membrane Interaction

ETIDOCAINE-A NEW LONG-ACTING LOCAL ANESTHETIC AGENT

1974 ◽  
Vol 18 (2) ◽  
pp. 182
Author(s):  
P. C. LUND ◽  
J. C. CWIK ◽  
R. T. PAGDANGANAN
Keyword(s):  
Local Anesthetic ◽  
Anesthetic Agent ◽  
Local Anesthetic Agent ◽  
Long Acting

scholarly journals Proof of pore formation and biophysical perturbations through a 2D amoxicillin-lipid membrane interaction approach

2017 ◽  
Vol 1859 (5) ◽  
pp. 803-812 ◽  
Author(s):  
Daniela Lopes ◽  
Cláudia Nunes ◽  
Philippe Fontaine ◽  
Bruno Sarmento ◽  
Salette Reis
Keyword(s):  
Pore Formation ◽  
Lipid Membrane ◽  
Membrane Interaction ◽  
Interaction Approach

Etidocaine—A New Long-Acting Local Anesthetic Agent

1973 ◽  
Vol 52 (3) ◽  
pp. 482-494 ◽  
Author(s):  
P. C. LUND ◽  
J. C. CWIK ◽  
R. T. PAGDANGANAN
Keyword(s):  
Local Anesthetic ◽  
Anesthetic Agent ◽  
Local Anesthetic Agent ◽  
Long Acting

scholarly journals Lipid Membrane Interaction of Peptide/DNA Complexes Designed for Gene Delivery

Langmuir ◽  
2021 ◽  
Vol 37 (5) ◽  
pp. 1882-1893
Author(s):  
Neval Yilmaz ◽  
Yutaka Kodama ◽  
Keiji Numata
Keyword(s):  
Gene Delivery ◽  
Lipid Membrane ◽  
Dna Complexes ◽  
Membrane Interaction
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