The human prion diseases: from neuropathology to pathobiology and molecular genetics

1997 ◽  
Vol 23 (5) ◽  
pp. 416-422 ◽  
Author(s):  
Herbert Budka
1999 ◽  
Vol 105 (3) ◽  
pp. 244-252 ◽  
Author(s):  
O. Windl ◽  
A. Giese ◽  
W. Schulz-Schaeffer ◽  
I. Zerr ◽  
K. Skworc ◽  
...  

Neurology ◽  
1994 ◽  
Vol 44 (12) ◽  
pp. 2347-2347 ◽  
Author(s):  
J.-L. Laplanche ◽  
N. Delasnerie-Laupretre ◽  
J. P. Brandel ◽  
J. Chatelain ◽  
P. Beaudry ◽  
...  

1999 ◽  
Vol 105 (3) ◽  
pp. 244-252 ◽  
Author(s):  
O. Windl ◽  
A. Giese ◽  
W. Schulz-Schaeffer ◽  
I. Zerr ◽  
K. Skworc ◽  
...  

1989 ◽  
Vol 12 (6) ◽  
pp. 221-227 ◽  
Author(s):  
David Westaway ◽  
George A. Carlson ◽  
Stanley B. Prusiner

Author(s):  
W. Bernard

In comparison to many other fields of ultrastructural research in Cell Biology, the successful exploration of genes and gene activity with the electron microscope in higher organisms is a late conquest. Nucleic acid molecules of Prokaryotes could be successfully visualized already since the early sixties, thanks to the Kleinschmidt spreading technique - and much basic information was obtained concerning the shape, length, molecular weight of viral, mitochondrial and chloroplast nucleic acid. Later, additonal methods revealed denaturation profiles, distinction between single and double strandedness and the use of heteroduplexes-led to gene mapping of relatively simple systems carried out in close connection with other methods of molecular genetics.


1992 ◽  
Vol 25 (5) ◽  
pp. 995-1009
Author(s):  
Michael J. Lanser
Keyword(s):  

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