Module placement with boundary constraints using B*-trees

J.-M. Lin; H.-E. Yi; Y.-W. Chang

doi:10.1049/ip-cds:20020433

Module placement with boundary constraints using B*-trees

IEE Proceedings - Circuits Devices and Systems ◽

10.1049/ip-cds:20020433 ◽

2002 ◽

Vol 149 (4) ◽

pp. 251-256 ◽

Cited By ~ 11

Author(s):

J.-M. Lin ◽

H.-E. Yi ◽

Y.-W. Chang

Keyword(s):

Boundary Constraints ◽

B Trees

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Supplemental Material for On the Likelihood Ratio Test in Structural Equation Modeling When Parameters Are Subject to Boundary Constraints

Psychological Methods ◽

10.1037/1082-989x.11.4.439.supp ◽

2006 ◽

Keyword(s):

Structural Equation Modeling ◽

Likelihood Ratio ◽

Likelihood Ratio Test ◽

Structural Equation ◽

Equation Modeling ◽

Ratio Test ◽

Boundary Constraints

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DEFOGGING OF IMAGE USING SPATIAL MRF WITH BOUNDARY CONSTRAINTS

i-manager’s Journal on Image Processing ◽

10.26634/jip.6.2.16447 ◽

2019 ◽

Vol 6 (2) ◽

pp. 28

Author(s):

DORA H. SIVACHANUKYA ◽

PRAKASH M. SUNIL ◽

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Keyword(s):

Boundary Constraints

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Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue

Science Advances ◽

10.1126/sciadv.abe9446 ◽

2021 ◽

Vol 7 (11) ◽

pp. eabe9446 ◽

Cited By ~ 1

Author(s):

Mark J. Mondrinos ◽

Farid Alisafaei ◽

Alex Y. Yi ◽

Hossein Ahmadzadeh ◽

Insu Lee ◽

...

Keyword(s):

Muscle Injury ◽

Cancer Cachexia ◽

Myogenic Differentiation ◽

Mechanical Anisotropy ◽

Musculoskeletal Tissue ◽

Boundary Constraints ◽

Cell Contractility ◽

Engineered Tissue ◽

Tissue Anisotropy

Here, we present an approach to model and adapt the mechanical regulation of morphogenesis that uses contractile cells as sculptors of engineered tissue anisotropy in vitro. Our method uses heterobifunctional cross-linkers to create mechanical boundary constraints that guide surface-directed sculpting of cell-laden extracellular matrix hydrogel constructs. Using this approach, we engineered linearly aligned tissues with structural and mechanical anisotropy. A multiscale in silico model of the sculpting process was developed to reveal that cell contractility increases as a function of principal stress polarization in anisotropic tissues. We also show that the anisotropic biophysical microenvironment of linearly aligned tissues potentiates soluble factor-mediated tenogenic and myogenic differentiation of mesenchymal stem cells. The application of our method is demonstrated by (i) skeletal muscle arrays to screen therapeutic modulators of acute oxidative injury and (ii) a 3D microphysiological model of lung cancer cachexia to study inflammatory and oxidative muscle injury induced by tumor-derived signals.

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