Does Addition of High-Dose Simethicone to Standard Bowel Preparation for Screening Colonoscopy Have an Effect on Adenoma Detection Rate: A Single-Blind Clinical Trial

2018 ◽  
Vol 155 (1) ◽  
pp. e43-e44
Author(s):  
Sharareh Moraveji ◽  
Nancy Casner ◽  
Alok Dwivedi ◽  
Mohammad Bashashati ◽  
Marc Zuckerman ◽  
...  
2012 ◽  
Vol 107 ◽  
pp. S812
Author(s):  
Praveen Guturu ◽  
Rajan Kochar ◽  
Bashar Hmoud ◽  
Sarat Jampana ◽  
Habeeb Salameh ◽  
...  

2018 ◽  
Vol 11 ◽  
pp. 117955221880330
Author(s):  
Sanna Fatima ◽  
Deepanshu Jain ◽  
Christopher Hibbard

Aim: To investigate the effect of video aid on quality of bowel preparation. Study: A retrospective study was done on patients undergoing outpatient screening colonoscopy. All subjects received educational video prior to colonoscopy in addition to the standard counseling. Patient charts were reviewed to collect data regarding quality of bowel preparation (adequate or inadequate). The study population was stratified into four groups according to viewing status: Group I 0% (control group), Group II <50%, Group III >50% to <75%, and Group IV watched ⩾75% of the video. Results: A total of 338 patients with an average age of 59.1 years and 60.3% females were included in the final study cohort. Of the patients in Groups I, II, III, and IV, 94.3%, 90.9%, 100%, and 91.7%, respectively, had adequate preparation ( P value = .827). Adenoma detection rate (ADR) for Groups I, II, III, and IV was 28.8%, 50%, 50%, and 22.6%, respectively ( P value = .305). The mean cecal intubation time was 20.7, 16.4, 16.57, and 17 minutes for Groups I, II, III, and IV, respectively ( P value = .041). Conclusions: Video aid use for patients undergoing screening colonoscopy lacked a statistically significant impact on the quality of bowel preparation, ADR, and advanced adenoma detection rate when compared with standard practice.


2017 ◽  
Vol 33 (3) ◽  
pp. 93-98 ◽  
Author(s):  
Jung Hun Park ◽  
Sang Jin Kim ◽  
Jong Hee Hyun ◽  
Kyung Su Han ◽  
Byung Chang Kim ◽  
...  

2011 ◽  
Vol 73 (4) ◽  
pp. AB395
Author(s):  
Tom J. Lee ◽  
Claire Nickerson ◽  
Colin Rees ◽  
Richard J. McNally ◽  
Matthew D. Rutter

Endoscopy ◽  
2017 ◽  
Author(s):  
Yu Bai ◽  
Jun Fang ◽  
Sheng-Bing Zhao ◽  
Dong Wang ◽  
Yan-Qing Li ◽  
...  

Abstract Background and study aims Ideal bowel preparation for colonoscopy requires complete removal of fluid and foam from the colon. Polyethylene glycol (PEG) is widely used for bowel preparation, with antifoaming agents such as simethicone commonly used in combination with PEG. Data on the effect of simethicone on the adenoma detection rate (ADR) were limited. This study therefore aimed to investigate whether preprocedure simethicone could increase the ADR. Patients and methods This was a prospective, multicenter, endoscopist-blinded randomized controlled trial involving consecutive patients who underwent colonoscopy in six centers in China. Patients were randomly assigned to one of two groups: PEG plus simethicone or PEG alone. The primary outcome was ADR; secondary outcomes were quality of bowel preparation, measured by the Boston bowel preparation scale (BBPS) and bubble scores. Results 583 patients were included. More adenomas were detected in the PEG plus simethicone group than in the PEG alone group (ADR 21.0 % vs. 14.3 %, P = 0.04; advanced ADR 9.0 % vs. 7.0 %, P = 0.38). The mean number of adenomas detected was 2.20 ± 1.36 vs. 1.63 ± 0.89 (P = 0.02). Patients in the PEG plus simethicone group showed better bowel cleansing efficacy: BBPS ≥ 6 in 88.3 % vs. 75.2 % (P < 0.001) and bubble scores of 1.00 ± 1.26 vs. 3.98 ± 2.50 (P < 0.001). Abdominal bloating was reported less frequently in the PEG plus simethicone group (7.8 % vs. 19.7 %, P < 0.001) than in the PEG alone group. Conclusion Combined use of PEG and simethicone is associated with a significantly increased ADR in a Chinese population.Clinical trials registration number: NCT02540239


2015 ◽  
Vol 148 (4) ◽  
pp. S-760
Author(s):  
Alicia M. Alvarez ◽  
Chau To ◽  
Kinchit Shah ◽  
Kanwarpreet S. Tandon ◽  
Seifeldin Hakim ◽  
...  

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