2018 ◽  
Vol 132 (11) ◽  
pp. 978-983 ◽  
Author(s):  
A E Pamuk ◽  
S Özer ◽  
A E Süslü ◽  
A Akgöz ◽  
M Önerci

AbstractObjectiveThis study aimed to present the clinical features and surgical outcomes of juvenile nasopharyngeal angiofibroma patients who were surgically treated.MethodsThe medical records of 48 male patients histologically confirmed as having juvenile nasopharyngeal angiofibroma, who underwent transnasal endoscopic surgery between 2005 and 2016, were retrospectively reviewed.ResultsThe overall recurrence rate was 20.8 per cent; however, the recurrence rate differed significantly between patients diagnosed aged less than 14 years (34.7 per cent) and more than 14 years (8 per cent) (p < 0.05). Advanced-stage tumours (Radkowski stage of IIC or more, and Önerci stage of III or more) were more aggressive than earlier stage tumours (p < 0.05 and p < 0.01, respectively). Pre-operative embolisation significantly prolonged mean hospitalisation duration, but had no effect on intra-operative blood loss in patients with advanced-stage tumours (p < 0.001 and p = 0.09, respectively).ConclusionThe findings show that transnasal endoscopic surgery could be considered the treatment of choice for juvenile nasopharyngeal angiofibroma. Patients diagnosed when aged less than 14 years and those with advanced-stage tumours are at risk of recurrence, and should be monitored with extreme care.


2021 ◽  
Vol 32 (01) ◽  
pp. 03-08
Author(s):  
Adeel Niaz ◽  
Muhammad Iqbal ◽  
Muhammad Ilyas ◽  
Ghulam Dastgir Khan ◽  
Riaz Ahmed Shahid ◽  
...  

ABSTRACT Introduction: Juvenile nasopharyngeal angiofibroma is a benign vasculartumor.It is commonly found in teen age males. Its site of origin is sphenopalatine foramen. Exact pathogenesis of angiofibroma is not known. It has predictable natural history and growth pattern. This tumor most often involves nasopharynx, nasal cavity, paranasal sinuses, pterygopalatine fossa and infratemporal fossa. It can also involve orbit and can spread intracranially. Its very important to diagnose this tumor very early on the basis of clinical examination and imaging. As early tumor confined to nose and sinuses can be removed exclusively with endoscope. It is very helpful to do angiography before surgery to ascertain itsblood supply and then embolization can be done to reduce intraoperative bleeding. Objective: To describe our experience of Juvenile Nasopharyngeal Angiofibroma cases in ENT Unit-I of Lahore General Hospital. Study Design: Descriptive Study with retrospective analysis after approval from Institutional Review Board (IRB) of LGH/PGMI/AMC Lahore. Methods: We studied 20 patients who underwent surgery in our department from October 2019 to October 2020. We analyzed following factors: age, gender, symptoms, staging, mode of surgery and need for intraoperative blood transfusion, hospital stay, complications and recurrences. Results: Range of patient’s age was 12 to 25 years. Eight patients underwent surgery with endoscope. Mean blood loss was about 400 ml and mean operating time was 140 minutes. All the cases were embolized preoperatively. Conclusion: Endoscopic surgery is a safe and effective method in early stage JNA patients. While patients with advance stage tumors should be managed with combined endoscopic and conventional open approaches. KEYWORDS: juvenile nasopharyngeal angiofibroma, JNA, endoscopic surgery  


2007 ◽  
Vol 137 (3) ◽  
pp. 492-496 ◽  
Author(s):  
Nilvano A. Andrade ◽  
José Antonio Pinto ◽  
Mônica de Oliveira Nóbrega ◽  
José Estelita P. Aguiar ◽  
Tâmara Ferraro A.P. Aguiar ◽  
...  

OBJECTIVE: To present the indications of nasal endoscopic surgery for treating juvenile nasopharyngeal angiofibroma (JNA). STUDY DESIGN: Chart review. MATERIALS AND METHODS: Twelve patients underwent nasal endoscopic surgery exclusively to resect JNA from January 2001 to June 2004. According to the classification of Andrews et al, eight patients were stage I and four patients were stage II. RESULTS: The follow-up was between five and 42 months, and no patient has shown a residual tumor or recurrence to date. CONCLUSION: In JNA stages I and II, the endoscopic approach was effective without preoperative arterial embolization. There were no residual tumors or recurrence in this study. SIGNIFICANCE: It seems to be appropriate to reevaluate the surgical limits of endoscopic surgery for resecting JNA.


Skull Base ◽  
2007 ◽  
Vol 17 (S 2) ◽  
Author(s):  
Trevor Hackman ◽  
Carl Snyderman ◽  
Ricardo Carrau ◽  
Amin Kassam

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