Human keratin 8 variants predispose to acetaminophen hepatotoxicity

2014 ◽  
Vol 52 (01) ◽  
Author(s):  
N Guldiken ◽  
Q Zhou ◽  
O Kucukoglu ◽  
M Rehm ◽  
LP James ◽  
...  
Keyword(s):  
Keratin 8 ◽  
Acetaminophen Hepatotoxicity

scholarly journals Human keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with c-jun amino-terminal kinase activation and protein adduct formation

Hepatology ◽  
2015 ◽  
Vol 62 (3) ◽  
pp. 876-886 ◽  
Author(s):  
Nurdan Guldiken ◽  
Qin Zhou ◽  
Ozlem Kucukoglu ◽  
Melanie Rehm ◽  
Kateryna Levada ◽  
...  
Keyword(s):  
Adduct Formation ◽  
Kinase Activation ◽  
Amino Terminal ◽  
Protein Adduct ◽  
Keratin 8 ◽  
Acetaminophen Hepatotoxicity

P1113 : Human Keratin 8 variants promote mouse acetaminophen hepatotoxicity coupled with JNK activation and protein adduct formation

2015 ◽  
Vol 62 ◽  
pp. S767-S768
Author(s):  
N. Guldiken ◽  
Q. Zhou ◽  
O. Kucukoglu ◽  
M. Rehm ◽  
K. Levada ◽  
...  
Keyword(s):  
Adduct Formation ◽  
Protein Adduct ◽  
Keratin 8 ◽  
Jnk Activation ◽  
Acetaminophen Hepatotoxicity

P316 HUMAN KERATIN 8 VARIANTS PREDISPOSE TO ACETAMINOPHEN HEPATOTOXICITY BUT NOT TO DEVELOPMENT OF CHOLESTATIC LIVER DISEASE

2014 ◽  
Vol 60 (1) ◽  
pp. S172
Author(s):  
N. Guldiken ◽  
Q. Zhou ◽  
O. Kucukoglu ◽  
M. Rehm ◽  
L.P. James ◽  
...  
Keyword(s):  
Liver Disease ◽  
Cholestatic Liver Disease ◽  
Keratin 8 ◽  
Acetaminophen Hepatotoxicity

Keratin 8 mutations in patient with cryptogenic liver disease

2001 ◽  
Vol 120 (5) ◽  
pp. A45-A45
Author(s):  
N KU ◽  
R GISH ◽  
T WRIGHT ◽  
M OMARY
Keyword(s):  
Liver Disease ◽  
Keratin 8

Acetaminophen Hepatotoxicity

Hepatology ◽  
2004 ◽  
Vol 40 (4) ◽  
pp. 1021-1021 ◽  
Author(s):  
Timothy J. Davern
Keyword(s):  
Acetaminophen Hepatotoxicity

Keratin-8-Mutationen prädisponieren nicht zur Entwicklung chronischer Lebererkrankungen insbesondere nicht zur kryptogenen Cirrhose

2015 ◽  
Vol 41 (08) ◽  
Author(s):  
J Halangk ◽  
T Berg ◽  
G Puhl ◽  
T Müller ◽  
O Landt ◽  
...  
Keyword(s):  
Keratin 8

scholarly journals Targeting CreERT2 expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis

2012 ◽  
Vol 21 (5) ◽  
pp. 1117-1123 ◽  
Author(s):  
Li Zhang ◽  
Boyu Zhang ◽  
Sang Jun Han ◽  
Amy N. Shore ◽  
Jeffrey M. Rosen ◽  
...  
Keyword(s):  
Bacterial Artificial Chromosome ◽  
Artificial Chromosome ◽  
Keratin 8
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