Domino Reactions of 1-Aroyl-3,4-dihydroisoquinolines with α,β-Unsaturated Aldehydes

Synthesis ◽  
2017 ◽  
Vol 49 (23) ◽  
pp. 5251-5257 ◽  
Author(s):  
Maria Matveeva ◽  
Tatiana Borisova ◽  
Alexander Titov ◽  
Lada Anikina ◽  
Svetlana Dyachenko ◽  
...  

An efficient synthesis of pyrrolo[2,1-a]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1-a]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported.

RSC Advances ◽  
2015 ◽  
Vol 5 (110) ◽  
pp. 90451-90456 ◽  
Author(s):  
Sundaravel Vivek Kumar ◽  
Shanmugam Muthusubramanian ◽  
Subbu Perumal

A facile synthesis of 4-hydroxy-3-arylthiazolidine-2-thiones through novel domino reactions of aryl isothiocyanates and 1,4-dithiane-2,5-diol under solvent- and catalyst-free microwave irradiation is reported.


2015 ◽  
Vol 13 (5) ◽  
pp. 1492-1499 ◽  
Author(s):  
Shakir Ahamad ◽  
Ashis Kumar Gupta ◽  
Ruchir Kant ◽  
Kishor Mohanan

A mild, efficient and rapid domino reaction involving the Bestmann–Ohira reagent (BOR) and α,β-unsaturated aldehydes has been developed for the synthesis of densely functionalized vinylpyrazoles.


Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 3045
Author(s):  
Guo-Ning Zhang ◽  
Xia Yuan ◽  
Weiping Niu ◽  
Mei Zhu ◽  
Juxian Wang ◽  
...  

A concise and efficient synthesis of acenaphtho[1,2-b]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Dalila Meziane ◽  
Abdelhamid Elias ◽  
Erwann Guénin

The aim of this investigation was to develop an efficient, rapid, and selective method for the synthesis ofω-alkylenediphosphoric acids (HO)2(O)P-O-CH2n-O-P(O)(OH)2from reaction of several diols with phosphorus oxychloride. The reaction was investigated using three methodologies: (i) presence of a base, (ii) classical heating, and (iii) use of microwave irradiation. Influence of reaction temperature and molar ratio of reagents, as well as the nature of the solvent, was studied using these three different methods.


ChemInform ◽  
2008 ◽  
Vol 39 (29) ◽  
Author(s):  
Qingqing Shao ◽  
Shujiang Tu ◽  
Chunmei Li ◽  
Longji Cao ◽  
Dianxiang Zhou ◽  
...  

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