Challenges and opportunities in sourcing for plant secondary metabolite research in the 21st century

Humanities research is extremely relevant for the challenges and opportunities of the 21st century. But despite the growing corpus of humanities research, there are few explicit translation mechanisms from academic work to broader communities. Building off of such a premise, this paper looks at where knowledge translation is occurring in other fields and what lessons might be learned for the wider and more efficient circulation of humanities work.

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Metabolic Engineering: A Strategy to Improve Plant Secondary Metabolite Production

Chemistry, Biological and Pharmacological Properties of Medicinal Plants from the Americas ◽

10.1201/9781315139272-12 ◽

2018 ◽

pp. 207-219

Author(s):

R. Verpoorte ◽

R. van der Heijden ◽

J. Memelink ◽

H.J.G. ten Hoopen

Keyword(s):

Metabolic Engineering ◽

Secondary Metabolite ◽

Secondary Metabolite Production ◽

Plant Secondary Metabolite ◽

Metabolite Production

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The 21st-century Maritime Silk Road: challenges and opportunities for transport management and practice

Transport Reviews ◽

10.1080/01441647.2018.1453562 ◽

2018 ◽

Vol 38 (4) ◽

pp. 413-415 ◽

Cited By ~ 10

Author(s):

Jasmine Siu Lee Lam ◽

Kevin Patrick Brendan Cullinane ◽

Paul Tae-Woo Lee

Keyword(s):

21St Century ◽

Silk Road ◽

Maritime Silk Road ◽

Challenges And Opportunities ◽

Transport Management

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Inhibition of Acetylcholinesterase and Butyrylcholinesterase by a Plant Secondary Metabolite Boldine

BioMed Research International ◽

10.1155/2018/9634349 ◽

2018 ◽

Vol 2018 ◽

pp. 1-5 ◽

Cited By ~ 8

Author(s):

Adam Kostelnik ◽

Miroslav Pohanka

Keyword(s):

Toxic Effect ◽

Secondary Metabolite ◽

Cholinesterase Inhibitor ◽

In Silico ◽

Chemical Compounds ◽

Spectrophotometric Assay ◽

Plant Secondary Metabolite ◽

Mechanism Of Inhibition ◽

In Silico Study ◽

Natural Alkaloid

Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are two enzymes sensitive to various chemical compounds having ability to bind to crucial parts of these enzymes. Boldine is a natural alkaloid and it was mentioned in some older works that it can inhibit some kinds of AChE. We reinvestigated this effect on AChE and also on BChE using acetyl (butyryl) thiocholine and Ellman’s reagents as standard substances for spectrophotometric assay. We found out IC50 of AChE equal to 372 μmol/l and a similar level to BChE, 321 μmol/l. We conclude our experiment by a finding that boldine is cholinesterase inhibitor; however we report significantly weaker inhibition than that suggested in literature. Likewise, we tried to investigate the mechanism of inhibition and completed it with in silico study. Potential toxic effect on cholinesterases in real conditions is also discussed.

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Ministry Amidst the Refugee Crisis in Europe: Understanding Missionary-Refugee Relationships

Transformation An International Journal of Holistic Mission Studies ◽

10.1177/02653788211048373 ◽

2021 ◽

pp. 026537882110483

Author(s):

Jamie N. Sanchez ◽

Leanne M. Dzubinski ◽

Jacqueline Parke

Keyword(s):

21St Century ◽

Research Question ◽

Structured Interview ◽

Refugee Crisis ◽

Main Research ◽

International Consultation ◽

Challenges And Opportunities

The purpose of this paper is to present the findings of an investigation into missionary-refugee relationships in Europe. The main research question guiding this study was: How do missionaries understand and describe their relationship with the refugees they serve? The data for this study were collected at an international consultation on ministry with refugees held in the fall of 2017 from 21 missionaries using semi-structured interview protocols. Findings demonstrate that missionaries shared a liminal identity with the refugees in their ministry, viewed hospitality as a Christian lifestyle, perceived Christianity to be an inclusive faith, and discussed the challenges and opportunities in their ministry with refugees. Based on the findings we offer implications for mission theorizing and practice in the 21st century church.

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