1,3-Dipolar Cycloaddition of Diethyl Nitromethylphosphonate, via the Nitrile Oxide, to Alkenes and 1-Alkenes. A Convenient One-Pot Synthesis of 3-Diethoxyphosphoryl-4,5-dihydroisoxazoles and 3-Diethoxyphosphorylisoxazoles

Synthesis ◽  
1990 ◽  
Vol 1990 (09) ◽  
pp. 817-819 ◽  
Author(s):  
Rongyu Zhang ◽  
Jian Chen
Author(s):  
Romana Pajkert ◽  
Henryk Koroniak ◽  
Pawel Kafarski ◽  
Gerd Volker Roeschenthaler

A one-pot, regioselective 1,3-dipolar cycloaddition of in situ generated (diethoxyphosphoryl)difluoromethyl nitrile oxide toward selected alkenes and alkynes is reported. This protocol enables facile access to 3,5-disubstituted isoxazolines and isoxazoles bearing...


2016 ◽  
Vol 22 (4) ◽  
Author(s):  
Khaoula Hajlaoui ◽  
Ahlem Guesmi ◽  
Naoufel Ben Hamadi ◽  
Moncef Msaddek

AbstractReadily prepared copper nanoparticles are an effective catalyst for 1,3-dipolar cycloaddition of carbohydrate azide and a variety of alkynes that furnishes the corresponding 1,2,3-triazole-sucrose derivatives in excellent yields. Products were screened for their antimycobacterial activity against


ChemInform ◽  
2009 ◽  
Vol 40 (30) ◽  
Author(s):  
Lidia S. Konstantinova ◽  
Kirill A. Lysov ◽  
Stanislav A. Amelichev ◽  
Natalia V. Obruchnikova ◽  
Oleg A. Rakitin

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