The Mannich Reaction Between Aromatic Ketones, Aromatic Aldehydes and Aromatic Amines

Synthesis ◽  
1991 ◽  
Vol 1991 (09) ◽  
pp. 717-718 ◽  
Author(s):  
Yi Lin ◽  
Lei Huangshu ◽  
Zou Junhua ◽  
Xu Xiujuan
RSC Advances ◽  
2014 ◽  
Vol 4 (71) ◽  
pp. 37941-37946 ◽  
Author(s):  
Daryoush Zareyee ◽  
Hamidreza Alizadeh

A mild, effective and green method for the Mannich reaction of aromatic aldehydes, aromatic amines and ketones has been accomplished in good to excellent yields using hydrophobic SBA-15-Ph-PrSO3H in water at room temperature.


1991 ◽  
Vol 23 (5) ◽  
pp. 673-676 ◽  
Author(s):  
Yi Lin ◽  
Zou Junhua ◽  
Lei Huangshu ◽  
Lin Xiaomei ◽  
Zhang Mingxiao

1991 ◽  
Vol 21 (20) ◽  
pp. 2109-2117 ◽  
Author(s):  
Yi Lin ◽  
Zou Junhua ◽  
Lei Huangshu ◽  
He Qilin

ChemInform ◽  
2010 ◽  
Vol 23 (8) ◽  
pp. no-no
Author(s):  
L. YI ◽  
J. ZOU ◽  
H. LEI ◽  
X. LIN ◽  
M. ZHANG

2012 ◽  
Vol 66 (1) ◽  
Author(s):  
S. Ozturkcan ◽  
Kadir Turhan ◽  
Zuhal Turgut

AbstractAn innovative, powerful, efficient and relatively rapid method was developed to synthesise various β-aminoketone derivatives from cyclohexanone, substituted aromatic amines and aromatic or hetero-aromatic aldehydes via ultrasound-assisted direct-type catalytic Mannich reaction using bismuth(III) triflate in water. Good yields of the desired β-aminoketones were obtained at room temperature by ultrasound-assisted reaction within 1–2 h. The major advantages of the proposed method are undemanding conditions, easy operation, low toxicity, shorter reaction time, anti selectivity and higher yields in comparison with conventional methods.


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