Kartagener’s Syndrome

2021 ◽  
pp. e45
Author(s):  
Kenneth Zurcher ◽  
Akira Kawashima
Author(s):  
George Price ◽  
Lizardo Cerezo

Ultrastructural defects of ciliary structure have been known to cause recurrent sino-respiratory infection concurrent with Kartagener's syndrome. (1,2,3) These defects are also known to cause infertility in both males and females. (4) Overall, the defects are defined as the Immotile, or Dyskinetic Cilia Syndrome (DCS). Several ultrastructural findings have been described, including decreased number of cilia, multidirection orientation, fused and compound cilia, membrane blebs, excess matrix in the axoneme, missing outer tubular doublets, translocated doublets, defective radial spokes and dynein arms. A rare but noteworthy ultrastructural finding in DCS is the predominance of microvilli-like structures on the luminal surface of the respiratory epithelium. (5,6) These permanent surface modifications of the apical respiratory epithelium no longer resemble cilia but reflect the ultrastructure of stereocilia, similar to that found in the epidydimal epithelium. Like microvilli, stereocilia are devoid of microtubular ultrastructure in comparison with true cilia.


1999 ◽  
Vol 173 (3) ◽  
pp. 822-822 ◽  
Author(s):  
J M Fonte ◽  
J D Varma ◽  
E Kuligowska

The Lancet ◽  
1978 ◽  
Vol 312 (8095) ◽  
pp. 893
Author(s):  
J CROFTON

1980 ◽  
Vol 89 (1) ◽  
pp. 81-83 ◽  
Author(s):  
Fred S. Herzon ◽  
Shirley Murphy

Kartagener's syndrome has been found to be associated with the immotile cilia syndrome (lack of dynein arms and defective radial spokes in cilia). The ultrastructure of cilia of a child with Kartagener's syndrome was examined and found to be within normal limits. The implications of this are discussed.


CHEST Journal ◽  
2008 ◽  
Vol 134 (4) ◽  
pp. 33P
Author(s):  
Nicola Ciancio ◽  
Margherita M. de Santi ◽  
Gianluca Battaglia ◽  
Benedetta Rossi ◽  
Lucia Spicuzza ◽  
...  

2004 ◽  
Vol 18 (1) ◽  
pp. 54-57 ◽  
Author(s):  
Yasuhiro Kouchi ◽  
Masatoshi Shigeta ◽  
Yuji Fujita ◽  
Hiroshi Miyashita

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