Transition metal mediated asymmetric synthesis. II. Complete resolution of (2R,5S)-(-)-Tricarbonyl[1-5-η-(2-methoxy-5-methylcyclohexadienyl)]iron(1+) hexafluorophosphate(1 -) by selective crystallization of enantiomers
Keyword(s):
The resolution of tricarbonyl(1-5-η-cylcohexadienyl)iron(1+) salts can be achieved by selective crystallization of enantiomers. The magnitude of the specific rotatory power of the title salt (1) was increased to a limiting value which was shown to correspond to optical purity, by a direct, n.m.r. method, after alkylation with dimethyl malonate. Reduction of the optically active salt defined the absolute configuration of (2R,5S)-(+ )-tricarbonyl[l-4-η-(2-methoxy-5β-methylcyclohexa-1,3-diene)]-iron(0). The chiroptical properties of the products are discussed.
1979 ◽
Vol 101
(6)
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pp. 1615-1617
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1975 ◽
Vol 40
(12)
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pp. 1843-1844
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1968 ◽
Vol 9
(56)
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pp. 5849-5852
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1973 ◽
Vol 95
(4)
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pp. 1217-1229
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Keyword(s):
1979 ◽
Vol 16
(4)
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pp. 667-672
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