scholarly journals Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors

2016 ◽  
Vol 291 (42) ◽  
pp. 21925-21944 ◽  
Author(s):  
Cathryn Weston ◽  
Ian Winfield ◽  
Matthew Harris ◽  
Rose Hodgson ◽  
Archna Shah ◽  
...  
2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
GOKÇEN TELLI ◽  
BANU CAHIDE TEL ◽  
BÜLENT GÜMÜSEL

1995 ◽  
Vol 269 (2) ◽  
pp. F141-F158 ◽  
Author(s):  
J. R. Raymond

The hormone-receptor-G protein complex transduces extracellular information into intracellular signals that ultimately regulate cellular functions in a highly specific manner. There are hundreds of receptor types that transduce signals through a relatively limited repertoire of heterotrimeric G proteins. Linear models of signaling specificity that require specific and highly selective coupling of hormone to receptor to G protein have proven inadequate to explain how highly particular signals are funneled through the G protein "bottleneck." Recent studies have uncovered a plethora of mechanisms that contribute to signaling specificity. This review focuses on the mechanisms that contribute to specificity in the interactions of receptors with G proteins.


2008 ◽  
Vol 150 (1) ◽  
pp. 78-84 ◽  
Author(s):  
Toru Kono ◽  
Takashi Koseki ◽  
Shinichi Chiba ◽  
Yoshiaki Ebisawa ◽  
Naoyuki Chisato ◽  
...  

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