Statistical analysis and physicochemical characteristics of groundwater ‎quality parameters: a case study

Author(s):  
Yaqoob Iqbal Memon ◽  
Sundus Saeed Qureshi ◽  
Imdad Ali Kandhar ◽  
Naeem Ahmed Qureshi ◽  
Sumbul Saeed ◽  
...  
Pharmaceutics ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 318 ◽  
Author(s):  
Jordi Ocaña ◽  
Toni Monleón-Getino ◽  
Virginia Merino ◽  
Daniel Peris ◽  
Lluís Soler

This study examines the statistical implications, and their possible implementation, of the “Draft guideline on quality and equivalence of topical products” issued by the European Medicines Agency in 2018, with particular focus on the section devoted to quality equivalence of physical properties. A new confidence interval to conduct the quality equivalence test and a way to cope with the multiplicity of quality parameters are presented and discussed. As an example, the results and the statistical analysis of a study on betamethasone 0.5 mg/g ointment are presented. It is suggested that the equivalence limits proposed in the draft guideline are overly strict: It is as difficult to declare quality equivalence between two packaging formats of the same reference product as to declare quality equivalence between the reference and the test product.


Author(s):  
Sundus Saeed Qureshi ◽  
Azizullah Channa ◽  
Sheeraz Ahmed Memon ◽  
Qamaruzaman Khan ◽  
Ghazala Akbar Jamali ◽  
...  

2021 ◽  
Vol 1058 (1) ◽  
pp. 012028
Author(s):  
Ahmed Khaleel Ibrahim ◽  
Salwa Hadi Ahmed ◽  
Ahmed Yasir Radeef ◽  
Massod Muhsin Hazzaa

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