scholarly journals Promising precision medicine: how patients, clinicians and caregivers work to realize the potential of genomics-informed cancer care

2021 ◽  
pp. 1-20
Author(s):  
Sara L. Ackerman
2021 ◽  
Author(s):  
Isabel Alvarado‐Cabrero ◽  
Franco Doimi ◽  
Virginia Ortega ◽  
Jurema Telles Oliveira Lima ◽  
Rubén Torres ◽  
...  

2019 ◽  
Vol 15 (6) ◽  
pp. 325-329 ◽  
Author(s):  
Laura A. Levit ◽  
Edward S. Kim ◽  
Barbara L. McAneny ◽  
Lincoln D. Nadauld ◽  
Kathryn Levit ◽  
...  

The use of precision medicine and the number of genomic-based treatments and immunotherapies is increasing. Nevertheless, oncology providers face challenges to implementing precision medicine, including in community practices, where most patients receive treatment. On January 31, 2018, ASCO hosted Precision Medicine: Expanding Opportunities, the inaugural event in ASCO’s new State of Cancer Care in America (SOCCA) event series. This article draws from the inaugural SOCCA event and the experiences of the SOCCA event participants to summarize the opportunities and challenges of precision medicine, and to highlight three successful models of implementing precision oncology in large, multisite community practices or networks: (1) Intermountain Healthcare, (2) Levine Cancer Institute, Atrium Health, and (3) National Cancer Care Alliance. The experience of these practices suggests that practice innovations that offer clinical decision support through molecular tumor boards and clinical pathways, and administrative support for prior authorization and clinical trial matching are key to successful implementation of large-scale, community-based precision medicine programs.


2021 ◽  
Vol 50 (8) ◽  
pp. 533-537
Author(s):  
Bogda Koczwara ◽  
Elysia Thornton-Benko ◽  
Richard J Cohn ◽  
Raymond J Chan ◽  
Joel Rhee ◽  
...  

Nature ◽  
2015 ◽  
Vol 520 (7547) ◽  
pp. 290-291 ◽  
Author(s):  
Mark A. Rubin

Author(s):  
Mindy Clyne ◽  
Amy Kennedy ◽  
Muin J. Khoury

Implementation science can be incorporated within genomics precision medicine research across the cancer care continuum. Cancer is at the forefront of precision medicine. To move the field forward, the use of implementation science frameworks, theories, models, strategies, and outcome measures is essential so that we can consistently explore how precision medicine discoveries are optimally integrated into care delivery systems. Learning health care systems are model systems for adoption, uptake, and sustainability of precision medicine throughout the cancer care continuum, with both systematic processes in place for research to inform practice, and capacity for a multilevel research agenda, including the utilization of implementation strategies across and among multiple levels. This chapter explores precision medicine across the cancer care continuum and describes implementation science challenges and opportunities.


2019 ◽  
Vol 9 (9) ◽  
pp. 1597-1610 ◽  
Author(s):  
Hossein Shooli ◽  
Habibollah Dadgar ◽  
Yì-Xiáng J Wáng ◽  
Manochehr Seyedi Vafaee ◽  
Saman Rassaei Kashuk ◽  
...  

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