molecular imaging
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2022 ◽  
Vol 453 ◽  
pp. 214333
Author(s):  
Huocheng Yang ◽  
Le Tu ◽  
Jie Li ◽  
Suya Bai ◽  
Zongxing Hu ◽  
...  
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2022 ◽  
pp. jnumed.121.262235
Author(s):  
Giri Krishnan ◽  
Nynke S van den Berg ◽  
Naoki Nishio ◽  
Shrey Kapoor ◽  
Jaqueline Pei ◽  
...  

2022 ◽  
Vol 8 ◽  
Author(s):  
Mitchel R. Stacy

Peripheral arterial disease (PAD) is an atherosclerotic disorder of non-coronary arteries that is associated with vascular stenosis and/or occlusion. PAD affecting the lower extremities is characterized by a variety of health-related consequences, including lifestyle-limiting intermittent claudication, ulceration of the limbs and/or feet, increased risk for lower extremity amputation, and increased mortality. The diagnosis of lower extremity PAD is typically established by using non-invasive tests such as the ankle-brachial index, toe-brachial index, duplex ultrasound, and/or angiography imaging studies. While these common diagnostic tools provide hemodynamic and anatomical vascular assessments, the potential for non-invasive physiological assessment of the lower extremities has more recently emerged through the use of magnetic resonance- and nuclear medicine-based approaches, which can provide insight into the functional consequences of PAD-related limb ischemia. This perspectives article specifically highlights and discusses the emerging applications of clinical nuclear medicine techniques for molecular imaging investigations in the setting of lower extremity PAD.


Author(s):  
Richárd Botár ◽  
Eniko Molnar ◽  
Zoltán Garda ◽  
Eniko Madarasi ◽  
Gyoergy Trencseny ◽  
...  

A new potential Zn(II) responsive Mn(II)-based MRI CA candidate derived form pyclen-3,9-diacetate (3,9-PC2A) has been synthesized possessing a di-(2-picolyl)amine (DPA) moiety as an active arm. The PC2A-DPA ligand was found...


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