Metered Dose Inhalers (MDIs) and Dry Powder Inhalers (DPIs) for Pulmonary Drug Delivery: CMC Issues

2005 ◽  
Vol 22 (1) ◽  
pp. 31-55 ◽  
Author(s):  
Devender S. Dhanda ◽  
Uday B. Kompella
Keyword(s):  
Drug Delivery ◽  
Pulmonary Drug Delivery ◽  
Dry Powder Inhalers ◽  
Metered Dose Inhalers ◽  
Dry Powder ◽  
Metered Dose

scholarly journals Medication Administration With Inhalers or Nebulizers

2021 ◽  
Vol 1 (11) ◽  
Author(s):  
Khai Than ◽  
Aleksandra Grobelna
Keyword(s):  
Clinical Effectiveness ◽  
Medication Administration ◽  
Chronic Obstructive ◽  
Dry Powder Inhalers ◽  
Metered Dose Inhalers ◽  
Dry Powder ◽  
Obstructive Pulmonary Disease ◽  
Metered Dose ◽  
The Cost ◽  
Evidence Based Guidelines

Delivery of medication via metered-dose inhalers to children or adults with asthma, or adults with chronic obstructive pulmonary disease at emergency departments or intensive care units, may be as effective as nebulizers in terms of clinical parameters and health care resource use. Limited data on adverse events showed no significant differences between metered-dose inhalers and nebulizers. No evidence was found on the clinical effectiveness of dry powder inhalers in comparison with nebulizers or metered-dose inhalers. No evidence was found on the cost-effectiveness of medication administration via metered-dose inhalers, nebulizers, or dry powder inhalers in comparison with each other. No evidence-based guidelines with recommendations regarding the comparative use of metered-dose inhalers, dry powder inhalers, or nebulizers for administration of medication were identified.

Equivalence testing and equivalence limits of metered-dose inhalers and dry powder inhalers measured by in vitro impaction

2000 ◽  
Vol 49 (3) ◽  
pp. 295-302 ◽  
Author(s):  
Marjolein Weda ◽  
Eduard R.M Geuns ◽  
Raymond C.R Vermeer ◽  
Nathalie R.A Buiten ◽  
Kirsten Hendriks-de Jong ◽  
...  
Keyword(s):  
Dry Powder Inhalers ◽  
Equivalence Testing ◽  
Metered Dose Inhalers ◽  
Dry Powder ◽  
Metered Dose

scholarly journals A Pathway From Porous Particle Technology Toward Tailoring Aerogels for Pulmonary Drug Administration

2021 ◽  
Vol 9 ◽  
Author(s):  
Thoa Duong ◽  
Clara López-Iglesias ◽  
Piotr K. Szewczyk ◽  
Urszula Stachewicz ◽  
Joana Barros ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Administration ◽  
Pulmonary Drug Delivery ◽  
Porous Particle ◽  
Dry Powder Inhalers ◽  
Dry Powder ◽  
Porous Particles ◽  
Particle Technology ◽  
Systemic Treatments

Graphical AbstractAerogel powders are advantageous porous particles in dry powder inhalers for the pulmonary drug delivery in local and systemic treatments.

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