Selection of single-isocenter for multiple-target stereotactic brain radiosurgery to minimize total margin volume

2020 ◽  
Vol 65 (18) ◽  
pp. 185012
Author(s):  
Jordan M Slagowski ◽  
Zhifei Wen
2018 ◽  
Vol 52 ◽  
pp. 73-74
Author(s):  
Georgia Prentou ◽  
Pantelis Karaiskos ◽  
Panagiotis Papagiannis ◽  
Evaggelos Pantelis ◽  
Efi Koutsouveli

2018 ◽  
Vol 19 (5) ◽  
pp. 651-658 ◽  
Author(s):  
Saeed Ahmed ◽  
Jeff Kapatoes ◽  
Geoffrey Zhang ◽  
Eduardo G. Moros ◽  
Vladimir Feygelman

Author(s):  
Leonie Brodbek ◽  
Jana Kretschmer ◽  
Katrin Büsing ◽  
Hui Khee Looe ◽  
Bjoern Poppe ◽  
...  

Abstract The RUBY head phantom in combination with the System QA insert MultiMet can be used for simultaneous point dose measurements at an isocentric and two off-axis positions. This study investigates the suitability of the system for systematic integral end-to-end testing of single-isocenter multiple target stereotactic treatments. Several volumetric modulated arc therapy plans were optimized on a planning CT of the phantom positioned in a stereotactic mask on the stereotactic treatment board. The plans were created for three artificial spherical target volumes centred around the measurement positions in the MultiMet insert. Target diameters between 5 and 40 mm were investigated. Coplanar and non-coplanar plans were optimized using the collapsed cone algorithm of the Oncentra Masterplan treatment planning system and recalculated with the Monte Carlo algorithm of the Monaco treatment planning system. Measurements were performed at an Elekta Synergy linear accelerator. The head phantom was positioned according to clinical workflow comprising immobilization and CBCT imaging. Simultaneous point dose measurements at all target positions were performed with three PinPoint 3D chambers (type 31022) as well as three microDiamond (type 60019) detectors and compared to the treatment planning system calculations. Furthermore, the angular dependence of the detector response was investigated to estimate the associated impact on the measured point dose values. Considering all investigated plans, PTV diameters and positions, the point doses calculated with the Monaco treatment planning system and the microDiamond measurements differed within 3.5%, whereas the PinPoint 3D showed differences of up to 6.9%. Point dose differences determined in comparison to the Oncentra Masterplan dose calculations were larger. The RUBY system was shown to be suitable for end-to-end testing of complex treatment scenarios such as single-isocenter multiple target plans.


2013 ◽  
Vol 40 (6Part19) ◽  
pp. 334-334
Author(s):  
R Popple ◽  
X Wu ◽  
Y Yuan ◽  
R Cardan ◽  
J Duan ◽  
...  

Author(s):  
Justin Roper ◽  
Vorakarn Chanyavanich ◽  
Gregory Betzel ◽  
Jeffrey Switchenko ◽  
Anees Dhabaan

2016 ◽  
Vol 28 (11) ◽  
pp. 1672-1687 ◽  
Author(s):  
Michael Jenkins ◽  
Anna Grubert ◽  
Martin Eimer

Previous research has shown that when two color-defined target objects appear in rapid succession at different locations, attention is deployed independently and in parallel to both targets. This study investigated whether this rapid simultaneous attentional target selection mechanism can also be employed in tasks where targets are defined by a different visual feature (shape) or when alphanumerical category is the target selection attribute. Two displays that both contained a target and a nontarget object on opposite sides were presented successively, and the SOA between the two displays was 100, 50, 20, or 10 msec in different blocks. N2pc components were recorded to both targets as a temporal marker of their attentional selection. When observers searched for shape-defined targets (Experiment 1), N2pc components to the two targets were equal in size and overlapped in time when the SOA between the two displays was short, reflecting two parallel shape-guided target selection processes with their own independent time course. Essentially the same temporal pattern of N2pc components was observed when alphanumerical category was the target-defining attribute (Experiment 2), demonstrating that the rapid parallel attentional selection of multiple target objects is not restricted to situations where the deployment of attention can be guided by elementary visual features but that these processes can even be employed in category-based attentional selection tasks. These findings have important implications for our understanding of the cognitive and neural basis of top–down attentional control.


Author(s):  
Juan‐Francisco Calvo‐Ortega ◽  
Peter B. Greer ◽  
Marcelino Hermida‐López ◽  
Sandra Moragues‐Femenía ◽  
Coral Laosa‐Bello ◽  
...  

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