In this article, we use BR0.3 type plate heat exchanger for experiment,and the heat transfer coefficient of the mixed plate heat exchanger is explored. Through the test platform of plate heat exchanger, a large number of experiments have been done in different mixed mode but the same passageway,and lots experimental data are obtained. By the linear fitting method and the analysis of the data, the main factors which influence the heat transfer coefficient of mixed plate heat exchanger were carried out,and the formula of heat transfer coefficient which fits at any mixed mode plate heat exchanger is obtained, to solve the problem of engineering calculation.The fact , there is no denying that the result which we get has great engineering significance