Consciousness Levels One Week after Admission to a Palliative Care Unit Improve Survival Prediction in Advanced Cancer Patients

2015 ◽  
Vol 18 (2) ◽  
pp. 170-175
Author(s):  
Jaw-Shiun Tsai ◽  
Chao-Hsien Chen ◽  
Chih-Hsun Wu ◽  
Tai-Yuan Chiu ◽  
Tatsuya Morita ◽  
...  
2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Francesca Nunziante ◽  
Silvia Tanzi ◽  
Sara Alquati ◽  
Cristina Autelitano ◽  
Enrica Bedeschi ◽  
...  

Abstract Background Dignity is a basic principle of palliative care and is intrinsic in the daily practice of professionals assisting individuals with incurable diseases. Dignity Therapy (DT) is a short-term intervention aimed at improving the sense of purpose, meaning and self-worth and at reducing the existential distress of patients facing advanced illness. Few studies have examined how DT works in countries of non-Anglo Saxon culture and in different real-life settings. Moreover, most studies do not provide detailed information on how DT is conducted, limiting a reliable assessment of DT protocol application and of its evaluation procedure. The aim of this study was to assess the feasibility and acceptability of a nurse-led DT intervention in advanced cancer patients receiving palliative care. Method This is a mixed-method study using before and after evaluation and semistructured interviews. Cancer patients referred to a hospital palliative care unit were recruited and provided with DT. The duration of sessions, and timeframes concerning each step of the study, were recorded, and descriptive statistical analyses were performed. The patients' dignity-related distress and feedback toward the intervention were assessed through the Patient Dignity Inventory and the Dignity Therapy Patient Feedback Questionnaire, respectively. Three nurses were interviewed on their experience in delivering the intervention, and the data were analyzed qualitatively. Results A total of 37/50 patients were enrolled (74.0%), of whom 28 (75.7%) completed the assessment. In 76.7% of cases, patients completed the intervention in the time limit scheduled in the study. No statistically significant reduction in the Patient Dignity Inventory scores was observed at the end of the intervention; most patients found DT to be helpful and satisfactory. Building opportunities for personal growth and providing holistic care emerged among the facilitators to DT implementation. Nurses also highlighted too great of a time commitment and a difficult collaboration with ward colleagues among the barriers. Conclusions Our findings strongly support the acceptability, but only partially support the feasibility, of nurse-led DT in advanced cancer patients in a hospital setting. Further research is needed on how to transfer the potential benefits of DT into clinical practice. Trial registration Retrospectively registered on ClinicalTrial.gov NCT04738305.


2016 ◽  
Vol 26 (10) ◽  
pp. 1463-1469 ◽  
Author(s):  
Weiwei Zhao ◽  
Zhenyu Wu ◽  
Jianhua Chen ◽  
Huixun Jia ◽  
Zhe Huang ◽  
...  

2017 ◽  
Vol 25 (7) ◽  
pp. 2147-2153 ◽  
Author(s):  
Sebastiano Mercadante ◽  
Claudio Adile ◽  
Patrizia Ferrera ◽  
Alessandra Casuccio

2018 ◽  
Vol 42 (1) ◽  
pp. 166 ◽  
Author(s):  
Chang Hyun Lee ◽  
Jong Kyu Kim ◽  
Hyun Jung Jun ◽  
Duk-Joo Lee ◽  
Wook Namkoong ◽  
...  

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. 11537-11537
Author(s):  
Tiago Pugliese Branco ◽  
Alze Pereira dos Santos Tavares ◽  
Mariana Sarkis Braz ◽  
Mariana Ribeiro Monteiro ◽  
Ana Beatriz Kinupe Abrahao ◽  
...  

11537 Background: Palliative Care Index (PPI) has been proposed to improve the accuracy of survival prediction for advanced cancer patients. The aim of this study is to investigate the feasibility and real-world prognosis survival of oncology inpatients from a Brazilian tertiary hospital using PPI. Methods: Hospitalized advanced cancer patients who have been referred to the Palliative Care Team were enrolled from May 2011 to December 2018. The PPI was collected within 24 hours of the referral by the palliative care physician. Primary endpoint was median overall survival (OS), estimated with the use of the Kaplan–Meier method, in three groups: PPI < 4.0; 4.0 ≤ PPI > 6.0 and PPI ≥ 6.0. Secondary endpoints were OS rate at 3-week for patients with PPI ≥ 6.0, and the most accurate PPI value to predict 6 and 3-week survival, calculated by ROC curve. Results: Total of 1.381 patients were included in this cohort with a median age of 68-year-old, and 51.3% of females. The most frequent primary cancer sites were lung/chest (17,2%), colorectal (14,3%), breast (11,2%), and biliopancreatic (10,9%). Among 454 patients with PPI < 4.0, median OS was 44 days (95% CI: 35,5-52,4); 20 days (95% CI: 15,4-24,5) for 260 patients with 4.0≤ PPI < 6.0 and 8 days (95% CI: 7-8,9) between 655 patients with PPI ≥ 6. Differences in OS among the groups adjusted for primary site, age and gender were significant (p < 0,001). OS rate at 3 weeks for PPI≥ 6.0 was 28.1% (OR 5,39 p < 0.001). PPI value of < 5,5 best predicted 6-week OS (79% sensibility, 55% specificity, AUC 0,714) and the PPI value of ≥ 5,5 predicted 3-week OS (67% sensibility, 73% specificity, AUC 0,753). Conclusions: PPI is feasible and suitable for routine clinical practice to predict survival among Brazilian patients with advanced cancer. In our study, PPI 5.5 seems to be the most accurate value to predict survival within 3 weeks.


2016 ◽  
Vol 25 (4) ◽  
pp. 1301-1306 ◽  
Author(s):  
Sebastiano Mercadante ◽  
Claudio Adile ◽  
Patrizia Ferrera ◽  
Francesco Masedu ◽  
Marco Valenti ◽  
...  

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