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2022 ◽  
Author(s):  
Jeanna Parsons Leigh ◽  
Chloe DeGrood ◽  
Alexandra Dodds ◽  
Francesca Rubulotta ◽  
Emily A. FitzGerald ◽  
...  

Abstract Purpose To understand critical care physician experiences across multiple countries with the COVID-19 pandemic to inform future pandemic preparedness planning. Methods In this qualitative study, 16 critical care physicians (from seven countries) identified in convenience, purposive sampling took part in individual semi-structured interviews from April 7, 2020 to August 27, 2020 that captured the first wave of the pandemic. Open coding was conducted by two researchers who facilitated inductive thematic analysis. Results Key themes identified following thematic analysis included: 1) sourcing and implementation of trusted information; 2) health systems-level preparedness with accessible supports; 3) institutional adaptations including changes to patient care; 4) professional safety and occupational wellbeing; 5) triage and restricted visitation policies; and 6) managing personal familial responsibilities. Conclusion Perspectives of critical care physicians are important for ongoing pandemic planning and should be included in future pandemic policy development.


2022 ◽  
Author(s):  
Nizan Shakarchy ◽  
Lucian Tatsa-Laur ◽  
Ron Kedem ◽  
Ariel Ben Yehuda ◽  
Leah Shelef

ABSTRACT Objective Severe suicide attempt is a major risk factor for completed suicide. The aim of the present study was to focus on suicide behavior and timing to gain better understanding of these populations. Method The nested case–control retrospective study based on medical records of 246,866 soldiers, who demonstrated suicide attempts of varying severity, including death by suicide were compared with soldiers who did not demonstrate such behavior. Results Risk for death by suicide was associated with males, military seniority of less than 12 months. High frequency of visits with mental health care professionals was associated with being severe suicide attempters (SAs). Moderate suicide attempts were associated with being a male, visiting a primary care physician frequently, and belonging to one of the two latest immigrant groups in Israel (Ethiopians and former Soviet Union). Mild suicide attempts were associated with having a psychiatric diagnosis on the enlistment day, visiting a mental health care professional at high or average frequency, visiting a primary care physician at high or average frequency, being a male, and being born in the former Soviet Union. While the proportion of males demonstrating suicidal behavior was higher than the females’, severe SAs were higher among females. There was a clear tendency of female suicide attempters at all levels to act toward the end of their military service. Conclusions Although half of the SAs were females, their characteristics may be similar to those of the male SAs, contrary to the sex differences in suicide behavior among civilians.


2022 ◽  
Author(s):  
health not provided

How Does The Optimal Max Keto Work? Optimal Max Keto is a weight reduction supplement that works by utilizing 100% unadulterated beta-hydroxybutyrate (BHB) ketones. Concentrates on show that taking BHB ketone salts can bring ketone step up in your circulatory system. Commonly, to drive yourself into a fat-consuming condition of "ketosis" without fasting or practicing is testing enough for everybody; except now there's Optimal Max Keto which guarantees a simpler way! It powers your body to go into a territory of Ketosis without the requirement for fasting or exercise. Optimal Max Keto, very much like numerous other Keto pills, utilizes different sorts of salts like calcium, magnesium, and sodium. These three minerals are fit for raising your ketones levels which powers the body to consume with smoldering heat any fats it has put away for energy as opposed to utilizing carbs. Fixings Found In Optimal Max Keto Optimal Max Keto contains regular parts. Here is a fast once-over of every part in Optimal Max Keto and how it functions. BHB Ketones (800mg): Optimal Max Keto contains three types of beta-hydroxybutyrate ketone salts. These salts incorporate Magnesium Beta Hydroxybutyrate, Calcium Beta Hydroxybutyrate, and Sodium Beta Hydroxybutyrate. Regardless, these salts are otherwise called BHB ketones and are fundamental in bringing the Ketone level up in our blood likewise that fasting and practicing do to your body. A solitary portion of Optimal Max Keto (Ketosis) contains a restrictive mix of these fixings. This is roughly 800 mg BHB ketones that assist you with arriving at your weight reduction objectives. As such, devouring BHB resembles assuming a weight reduction alternate way since you won't have to practice quick or follow any severe dietary arrangement. Optimal Max Keto Negative Effects: There's consistently a chance of unfriendly responses occurring in the main long stretches of utilizing a thing like this. 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To buy your provisions, submit a request through Optimal Max Keto set up site. Continuously buy straightforwardly from the maker assuming you are capable! At the point when you are aware of a person who can be looking to place the item into their life ensure they've look at this assessment as well. Use the switches on the right to frontward them the Optimal Max Keto outline right now. Much obliged for checking out and best needs on the prosperity! As indicated by its marking, Optimal Max Keto Reviews is a result of KP Commerce, LLC, an enhancements organization. The item is a weight reduction equation that assists the body with entering the province of Ketosis in a more limited time and with less exertion than eating less junk food. Tragically, there isn't a lot of data about its maker or maker, yet here is the thing that we know: End Optimal Max Keto can be probably the most ideal decision for anybody hoping to get in shape without slimming down or working out. Notwithstanding, the organization suggests faster outcomes by watching what you eat and getting into a basic exercise standard, like strolling. This can assist with the speed and effectiveness of the whole weight reduction process.


2022 ◽  
pp. 28-33
Author(s):  
Oksana Anatolievna Gizinger ◽  
◽  
Irina Yurievna Lepina ◽  
Marina Nikolaevna Bagdasaryan ◽  
◽  
...  

The article analyzes the pathogenetic features of bacterial meningitis and substantiates the scheme of complex therapy of the disease using the recombinant cytokine interleukin-2 (IL2). The clinical, immunological and microbiological efficacy of the complex therapy scheme has been revealed. It has been shown that the pleiotropic effects of recombinant IL-2, its effect on the activity of metabolic processes at the cellular and subcellular levels, the ability to stabilize the system of lipid peroxidation of cell membranes, the ability to influence the processes of clonal proliferation and differentiation of T- and B-lymphocytes, make its use justified in complex therapy of meningitis.


Hand ◽  
2021 ◽  
pp. 155894472110604
Author(s):  
Kamilcan Oflazoglu ◽  
Elfi M. Verheul ◽  
Taylor M. Pong ◽  
Marco J. F. P. Ritt ◽  
Hinne Rakhorst ◽  
...  

Background: The aim was to determine the threshold Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) score that estimates a diagnosis of major depression in patients with fingertip injuries in American and Dutch patients. Methods: In this observational cross-sectional study, 112 patients with a recent fingertip injury measured symptoms of depression with the Patient Health Questionnaire and upper extremity disability with the QuickDASH. Results: In the US cohort, 8 of 56 patients had an estimated diagnosis of major depression. A threshold value of QuickDASH of 50 showed a sensitivity of 88% and a specificity of 81%, with a negative predicting value (NPV) of 95% for an estimated diagnosis of major depression. In the Dutch cohort, 7 of 56 patients had an estimated diagnosis of major depression. The same threshold score of 50 had a sensitivity of 71%, a specificity of 63%, and an NPV of 94%. Conclusions: We have found a correlation between experienced loss of function and an estimated diagnosis of major depression in patients with a fingertip injury. Referral to the primary care physician for further evaluation of depression in these patients is advised.


Author(s):  
А.Л. Кебина ◽  
А.С. Сычёва ◽  
А.Л. Вёрткин ◽  
Г.Ю. Кнорринг

Злокачественные заболевания остаются важной проблемой медицины, при этом ее решение зависит от эффективности выявления ранних стадий онкозаболеваний на амбулаторном этапе, включая терапевтическое звено оказания медицинской помощи. Существующие в настоящее время подходы к пропаганде основ здорового образа жизни преимущественно направлены лишь на профилактику поведенческих факторов риска: табакокурения, нерационального питания, недостаточной физической активности и пагубного употребления алкоголя. При этом, по оценкам экспертов, даже воздействие только на них позволит предотвратить по меньшей мере 40% случаев развития злокачественных новообразований. В России организована 3-уровневая система оказания медицинской помощи. Именно первый уровень оказания первичной медико-санитарной помощи и должен обеспечивать профилактическую направленность здравоохранения: грамотная диспансеризация способна обеспечить существенный, до 30%, вклад в снижение общей смертности населения, в том числе и смертности от злокачественных новообразований. Первым звеном диагностики онкологического заболевания являются терапевты, к которым пациенты обращаются с жалобами общего характера (утомляемость, субфебрилитет, боли в суставах, дизурия и т. д.). Наиболее актуальными задачами в работе терапевта являются своевременное обнаружение опухолевого заболевания и направление больного на лечение к онкологу. Статья рассматривает возможности скрининговых мероприятий с участием терапевтов, врачей общей практики, предлагает специально разработанные алгоритмы диагностики доброкачественных и злокачественных новообразований предстательной железы. Формирование навыков онкологической настороженности у врача первичного амбулаторного звена необходимо для раннего выявления и снижения частоты продвинутых стадий опухолей и более раннего начала специализированного лечения. Выявление симптоматики, подозрительной на злокачественные новообразования, с помощью алгоритмизированных подходов и последующая консультация пациента урологом или онкологом должны улучшить результаты лечения. Malignant diseases remain an important problem in medicine, while its solution depends on the effectiveness of detecting the early stages of cancer at the outpatient stage, including the therapeutic link in the provision of medical care. Currently existing approaches to the promotion of the foundations of a healthy lifestyle are mainly aimed only at the prevention of behavioral risk factors: tobacco smoking, unhealthy diet, insufficient physical activity and harmful use of alcohol. At the same time, according to experts, even exposure only to them will prevent at least 40% of cases of the development of malignant ovariances. A 3-tier system of medical care has been organized in Russia. It is the first level of primary health care that should ensure the prophylactic focus of health care: competent clinical examination is able to provide a significant, up to 30%, contribution to reducing the overall mortality of the population, including mortality from malignant neoplasms. The first stage in the diagnosis of oncological disease are therapists, to whom patients come with general complaints (fatigue, low-grade fever, joint pain, dysuria, etc.). The most urgent task in the work of a general practitioner is the timely detection of a tumor disease and referral of a patient for treatment to an oncologist. The article considers the possibilities of screening measures with the participation of therapists, general practitioners, and offers specially developed algorithms for the diagnosis of benign and malignant neoplasms of the prostate gland. The formation of oncological alertness skills in a primary outpatient care physician is necessary for early detection and reduction of the incidence of advanced stages of tumors and earlier initiation of specialized treatment. Identification of symptoms suspicious of malignant neoplasms using algorithmic approaches and subsequent consultation with the patient by a specialist urologist or oncologist should improve treatment outcomes.


Author(s):  
Suraj Pai ◽  
Tracy Andrews ◽  
Amber Turner ◽  
Aziz Merchant ◽  
Michael Shapiro

Background: Medical advances prolong life and treat illness but many patients have chronically debilitating conditions that prevent them from making end-of-life (EOL) decisions for themselves. These situations are difficult to navigate for both patient and physician. This study investigates physicians’ feelings and approach toward EOL care, physician-assisted suicide (PAS), and euthanasia. Methods: An anonymous, self-administered online survey was distributed through the New Jersey Medical School servers and American College of Surgeons forums. The survey presented clinical EOL vignettes and subjective questions regarding PAS and euthanasia. Results: We obtained 142 responses from attending physicians. Respondents were typically male (61%), married (85%), identified as Christian (54%), had more than 20 years of experience (55%), and worked at a university hospital (57%). Religious beliefs and years of work experience seemed to be significant contributors in EOL decision making, whereas gender and medical specialty were not significantly influential. Conclusion: Factors such as years of work experience and religious belief may influence medical professionals’ opinions about PAS and euthanasia and their subsequent actions regarding EOL care. In many cases, the boundaries are blurred and require further study before concrete conclusions can be made.


2021 ◽  
Author(s):  
David Ung ◽  
Yun Wang ◽  
Vijaya Sundararajan ◽  
Derrick Lopez ◽  
Monique F. Kilkenny ◽  
...  

Background and Purpose: Primary care physicians provide ongoing management after stroke. However, little is known about how best to measure physician encounters with reference to longer term outcomes. We aimed to compare methods for measuring regularity and continuity of primary care physician encounters, based on survival following stroke using linked healthcare data. Methods: Data from the Australian Stroke Clinical Registry (2010-2014) were linked with Australian Medicare claims from 2009 2016. Physician encounters were ascertained within 18 months of discharge for stroke. We calculated three separate measures of continuity of encounters (consistency of visits with primary physician) and three for regularity of encounters (distribution of service utilization over time). Indices were compared based on 1-year survival using multivariable Cox regression models. The best performing measures of regularity and continuity, based on model fit, were combined into a composite ‘optimal care’ variable. Results: Among 10,728 registrants (43% female, 69% aged ≥65 years), the median number of encounters was 17. The measures most associated with survival (hazard ratio [95% confidence interval], Akaike information criterion [AIC], Bayesian information criterion [BIC]) were the: Continuity of Care Index (COCI, as a measure of continuity; 0.88 [0.76 1.02], p=0.099, AIC=13746, BIC=13855) and our persistence measure of regularity (encounter at least every 6 months; 0.80 [0.67 0.95], p=0.011, AIC=13742, BIC=13852). Our composite measure, persistent plus COCI ≥80% (24% of registrants; 0.80 [0.68 0.94], p=0.008, AIC=13742, BIC=13851), performed marginally better than our persistence measure alone. Conclusions: Our persistence measure of regularity or composite measure may be useful when measuring physician encounters following stroke.


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