Hemodynamic and Endocrinological Effects of a New Selective  1-Blocking Agent, Terazosin, in Patients With Essential Hypertension Results of Long-Term Treatment

1989 ◽  
Vol 2 (11 Pt 1) ◽  
pp. 834-839 ◽  
Author(s):  
F. Tomoda ◽  
M. Takata ◽  
K. Yoshida ◽  
K. Yasumoto ◽  
M. Mikawa ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Blocking Agent ◽  
Term Treatment ◽  
Long Term Treatment

Haemodynamic Effects of Withdrawal of Long-Term Treatment with β-Adrenoceptor Blocking Agents in Subjects with Essential Hypertension

1981 ◽  
Vol 61 (s7) ◽  
pp. 421s-423s ◽  
Author(s):  
C. Bengtsson ◽  
Y. Larsson ◽  
V. Panfilov ◽  
R. Sivertsson ◽  
H. Åström
Keyword(s):  
Blood Pressure ◽  
Cardiac Output ◽  
Essential Hypertension ◽  
Structural Changes ◽  
Peripheral Resistance ◽  
Blocking Agent ◽  
Term Treatment ◽  
First Year ◽  
Long Term Treatment

1. After 10 years of β-adrenoceptor blockade in five female patients with essential hypertension, the β-adrenoceptor-blocking agent was withdrawn, and the women were then followed up for 1 year, with measurements of cardiac output and peripheral resistance. 2. Blood pressure remained low during the first year after withdrawal in spite of the fact that the heart rate increased within the first few days. 3. Cardiac output was found to increase during the first year after withdrawal, although total peripheral resistance was essentially unchanged. 4. The maintenance of low blood pressure after withdrawal of the antihypertensive drug might indicate a regression of structural changes in the resistance vessels during successful long-term antihypertensive treatment. 5. Minimal resistance in hands and calves did not increase during the year after withdrawal.

Increased Plasma Noradrenaline Concentrations in Essential Hypertension and Their Decrease after Long-Term Treatment with a β-Receptor-Blocking Agent (Prindolol)

1976 ◽  
Vol 51 (s3) ◽  
pp. 485s-488s ◽  
Author(s):  
H. M. Brecht ◽  
F. Banthien ◽  
W. Ernst ◽  
W. Schoeppe
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Nervous Activity ◽  
Blocking Agent ◽  
Term Treatment ◽  
Plasma Noradrenaline ◽  
Sympathetic Nervous Activity ◽  
Control Subjects ◽  
Long Term Treatment

1. Plasma noradrenaline was measured in fiftynine patients with mild to severe essential hypertension and in fifteen normotensive control subjects under basal and orthostatic conditions. 2. In patients with essential hypertension mean plasma noradrenaline concentrations were significantly higher than in control subjects under basal and orthostatic conditions. 3. In patients with essential hypertension basal diastolic blood pressure correlated closely with the corresponding plasma noradrenaline concentrations. 4. Long-term treatment with prindolol of patients with essential hypertension led to a significant fall in diastolic and systolic blood pressure and heart rate and to a significant decrease in plasma noradrenaline concentrations under basal and orthostatic conditions. 5. The adrenergic response to upright posture, reflected by an increase in plasma noradrenaline, was not abolished by prindolol. 6. It is concluded that the anti-hypertensive effect of prindolol in patients with essential hypertension is at least partially mediated by a decrease of sympathetic nervous activity.

Terazosin, A New Selective  1-Adrenergic Blocking Agent: Results of Long-Term Treatment in Patients with Essential Hypertension

1988 ◽  
Vol 1 (3 Pt 3) ◽  
pp. 237S-240S ◽  
Author(s):  
R. R. Luther ◽  
H. N. Glassman ◽  
C. B. Estep ◽  
P. J. Schmitz ◽  
J. K. Horton ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Blocking Agent ◽  
Term Treatment ◽  
Long Term Treatment ◽  
Adrenergic Blocking

Efficacy and Tolerability of Muzolimine in the Long-Term Treatment of Essential Hypertension

1987 ◽  
pp. 317-319 ◽  
Author(s):  
M. Carnovali ◽  
C. Borgnino ◽  
E. Crespi ◽  
M. Panozzo ◽  
A. Missaglia ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Long Term Treatment

Long term treatment of moderate hypertension with the beta1-receptor blocking agent metoprolol

1977 ◽  
Vol 11 (4) ◽  
pp. 247-254 ◽  
Author(s):  
B. -G. Hansson ◽  
J. -F. Dymling ◽  
P. Manhem ◽  
B. H�kfelt
Keyword(s):  
Moderate Hypertension ◽  
Blocking Agent ◽  
Term Treatment ◽  
Receptor Blocking ◽  
Long Term Treatment

Complications in long term treatment of essential hypertension

2009 ◽  
Vol 209 (S646) ◽  
pp. 123-126
Author(s):  
H. Løken ◽  
H. & Hebnes ◽  
K. Diakonissesykehus
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Long Term Treatment

scholarly journals Long-term treatment of essential hypertension using nadolol and hydrochlorothiazide combined.

1979 ◽  
Vol 7 (S2) ◽  
pp. 199S-203S ◽  
Author(s):  
MM El-Mehairy ◽  
A Shaker ◽  
M Ramadan ◽  
S Hamza ◽  
SS Tadros
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Long Term Treatment

Haemodynamic and clinical effects of long-term treatment of essential hypertension with captopril

1983 ◽  
Vol 4 (7) ◽  
pp. 496-501 ◽  
Author(s):  
B. RICCIARDELLI ◽  
M. VOLPE ◽  
B. TRIMARCO ◽  
N. DE LUCA ◽  
A. CUOCOLO ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Term Treatment ◽  
Clinical Effects ◽  
Long Term Treatment
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