scholarly journals Phase I/II study of combined BCL-XL and MEK inhibition with navitoclax (N) and trametinib (T) in KRAS or NRAS mutant advanced solid tumours

2019 ◽  
Vol 30 ◽  
pp. v164 ◽  
Author(s):  
R.B. Corcoran ◽  
K.T. Do ◽  
J.M. Cleary ◽  
A.R. Parikh ◽  
O.O. Yeku ◽  
...  
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Solid Tumours ◽  
Mek Inhibition

Intravenous administration of CP-4055 (ELACYT™) in patients with solid tumours. A phase I study

2009 ◽  
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pp. 137-145 ◽  
Author(s):  
Svein Dueland ◽  
Steinar Aamdal ◽  
Michael J. Lind ◽  
Hilary Thomas ◽  
Marit Liland Sandvold ◽  
...  
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Intravenous Administration ◽  
Phase I Study ◽  
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scholarly journals Phase I safety and pharmacokinetic study of SU-014813 in combination with docetaxel in patients with advanced solid tumours

2011 ◽  
Vol 47 (9) ◽  
pp. 1328-1335 ◽  
Author(s):  
M.J.A. de Jonge ◽  
H. Dumez ◽  
J.J.E.M. Kitzen ◽  
B. Beuselinck ◽  
J. Verweij ◽  
...  
Keyword(s):  
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Pharmacokinetic Study ◽  
Solid Tumours

1247 POSTER Phase I, Pharmacokinetics (PK), Pharmacodynamic (PD) Study of Lapatinib (L) in Combination With Sorafenib (S) in Patients With Advanced Refractory Solid Tumours

2011 ◽  
Vol 47 ◽  
pp. S159
Author(s):  
M. Simonelli ◽  
P.A. Zucali ◽  
R. De Sanctis ◽  
E. Lorenzi ◽  
F. De Vincenzo ◽  
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1246 POSTER A Phase I Dose-escalation Study of EMD 1214063, an Oral Selective C-Met Inhibitor, in Patients With Advanced Solid Tumours

2011 ◽  
Vol 47 ◽  
pp. S158
Author(s):  
G.S. Falchook ◽  
S. Fu ◽  
H.M. Amin ◽  
S.A. Piha-Paul ◽  
D.S. Hong ◽  
...  
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Dose Escalation Study ◽  
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scholarly journals A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours

2013 ◽  
Vol 108 (5) ◽  
pp. 1061-1070 ◽  
Author(s):  
M A Warso ◽  
J M Richards ◽  
D Mehta ◽  
K Christov ◽  
C Schaeffer ◽  
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Keyword(s):  
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A phase I, dose-escalation study of the novel Polo-like kinase inhibitor volasertib (BI 6727) in patients with advanced solid tumours

2012 ◽  
Vol 48 (2) ◽  
pp. 179-186 ◽  
Author(s):  
Patrick Schöffski ◽  
Ahmad Awada ◽  
Herlinde Dumez ◽  
Thierry Gil ◽  
Sylvie Bartholomeus ◽  
...  
Keyword(s):  
Phase I ◽  
Dose Escalation ◽  
Kinase Inhibitor ◽  
Solid Tumours ◽  
The Novel ◽  
Dose Escalation Study
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