A Respiratory Syncytial Virus Vaccine Based on the Small Hydrophobic Protein Ectodomain Presented With a Novel Lipid-Based Formulation Is Highly Immunogenic and Safe in Adults: A First-in-Humans Study

Virus Vaccine ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Small Hydrophobic ◽

Respiratory Syncytial Virus Vaccine ◽

Lipid Based Formulation

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein

EMBO Molecular Medicine ◽

10.15252/emmm.201404005 ◽

2014 ◽

Vol 6 (11) ◽

pp. 1436-1454 ◽

Cited By ~ 35

Author(s):

Bert Schepens ◽

Koen Sedeyn ◽

Liesbeth Vande Ginste ◽

Sarah De Baets ◽

Michael Schotsaert ◽

...

Keyword(s):

Mechanism Of Action ◽

Virus Vaccine ◽

Vaccine Candidate ◽

Extracellular Domain ◽

Hydrophobic Protein ◽

Respiratory Syncytial Virus Vaccine

Syncytial Virus ◽

Small Hydrophobic ◽

Nucleotide sequence analysis of a matrix and small hydrophobic protein dicistronic mRNA of bovine respiratory syncytial virus demonstrates extensive sequence divergence of the small hydrophobic protein from that of human respiratory syncytial virus

Journal of General Virology ◽

10.1099/0022-1317-72-7-1715 ◽

1991 ◽

Vol 72 (7) ◽

pp. 1715-1720 ◽

Cited By ~ 19

Author(s):

S. K. Samal ◽

M. Zamora

Keyword(s):

Sequence Analysis ◽

Nucleotide Sequence ◽

Sequence Divergence ◽

Nucleotide Sequence Analysis ◽

Hydrophobic Protein ◽

Extensive Sequence ◽

Syncytial Virus ◽

Structural and functional characterization of the human respiratory syncytial virus small hydrophobic protein

10.32657/10356/42676 ◽

2010 ◽

Author(s):

Siok Wan Gan

Keyword(s):

Functional Characterization ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Modulation of the transcription factor NF-κB in antigen-presenting cells by bovine respiratory syncytial virus small hydrophobic protein

Journal of General Virology ◽

10.1099/jgv.0.000855 ◽

2017 ◽

Vol 98 (7) ◽

pp. 1587-1599 ◽

Cited By ~ 8

Author(s):

Nicola Pollock ◽

Geraldine Taylor ◽

Fatoumatta Jobe ◽

Efrain Guzman

Keyword(s):

Transcription Factor ◽

Antigen Presenting Cells ◽

Bovine Respiratory Syncytial Virus ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Antigen Presenting ◽

Membrane orientation and oligomerization of the small hydrophobic protein of human respiratory syncytial virus

Journal of General Virology ◽

10.1099/0022-1317-74-7-1445 ◽

1993 ◽

Vol 74 (7) ◽

pp. 1445-1450 ◽

Cited By ~ 50

Author(s):

P. L. Collins ◽

G. Mottet

Keyword(s):

Membrane Orientation ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen

Immunotherapy ◽

10.2217/imt.15.11 ◽

2015 ◽

Vol 7 (3) ◽

pp. 203-206 ◽

Cited By ~ 6

Author(s):

Bert Schepens ◽

Michael Schotsaert ◽

Xavier Saelens

Keyword(s):

Vaccine Antigen ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

The Small Hydrophobic Protein of the Human Respiratory Syncytial Virus Forms Pentameric Ion Channels

Journal of Biological Chemistry ◽

10.1074/jbc.m111.332791 ◽

2012 ◽

Vol 287 (29) ◽

pp. 24671-24689 ◽

Cited By ~ 76

Author(s):

Siok-Wan Gan ◽

Edward Tan ◽

Xin Lin ◽

Dejie Yu ◽

Juejin Wang ◽

...

Keyword(s):

Ion Channels ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Direct visualization of the small hydrophobic protein of human respiratory syncytial virus reveals the structural basis for membrane permeability

FEBS Letters ◽

10.1016/j.febslet.2010.05.006 ◽

2010 ◽

Vol 584 (13) ◽

pp. 2786-2790 ◽

Cited By ~ 42

Author(s):

Stephen D. Carter ◽

Kyle C. Dent ◽

Elizabeth Atkins ◽

Toshana L. Foster ◽

Mark Verow ◽

...

Keyword(s):

Membrane Permeability ◽

Structural Basis ◽

Direct Visualization ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Modeling the structure of the respiratory syncytial virus small hydrophobic protein by silent-mutation analysis of global searching molecular dynamics

Protein Science ◽

10.1110/ps.03151103 ◽

2003 ◽

Vol 12 (12) ◽

pp. 2668-2674 ◽

Cited By ~ 19

Author(s):

Uzi Kochva ◽

Hadas Leonov ◽

Isaiah T. Arkin

Keyword(s):

Molecular Dynamics ◽

Mutation Analysis ◽

Silent Mutation ◽

Hydrophobic Protein ◽

Syncytial Virus ◽

Inhibition of the Human Respiratory Syncytial Virus Small Hydrophobic Protein and Structural Variations in a Bicelle Environment

Journal of Virology ◽

10.1128/jvi.00839-14 ◽

2014 ◽

Vol 88 (20) ◽

pp. 11899-11914 ◽

Cited By ~ 31

Author(s):

Y. Li ◽

J. To ◽

C. Verdia-Baguena ◽

S. Dossena ◽

W. Surya ◽

...

Keyword(s):

Structural Variations ◽

Hydrophobic Protein ◽

Syncytial Virus ◽