Malignant Marrow Bone Tumors

2019 ◽  
pp. 293-300
Author(s):  
Jonathan D. Samet
Keyword(s):  
Bone Marrow ◽  
Bone Tumors ◽  
Patient Management ◽  
Practical Approach ◽  
Bone Marrow Lesions ◽  
Bone Marrow Signal ◽  
Malignant Lesions ◽  
Marrow Signal

Chapter 59 discusses malignant bone marrow tumors. Musculoskeletal radiologists are frequently confronted with bone marrow signal alterations on MRI that may represent physiologic variations or benign or malignant lesions. Although statistically most of these bone marrow signal abnormalities will be benign, distinguishing malignant from benign bone marrow entities is critical to patient management. This differentiation is not always possible on imaging, however, and biopsy may be necessary. This chapter will provide a practical approach to interpretation of diffuse and focal bone marrow abnormalities with an emphasis on malignant bone marrow lesions. With particular MRI criteria discussed, the reader will gain confidence in identifying malignant lesions and know for which lesions to recommend biopsy.

Bone Marrow Signal Alteration in the Spine and Sacrum

2010 ◽  
Vol 195 (3) ◽  
pp. W178-W200 ◽  
Author(s):  
Suzanne S. Long ◽  
Corrie M. Yablon ◽  
Ronald L. Eisenberg
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Signal ◽  
Marrow Signal

scholarly journals MR imaging of the foot and ankle: patterns of bone marrow signal abnormalities

2001 ◽  
Vol 12 (2) ◽  
pp. 416-426 ◽  
Author(s):  
Dominik Weishaupt ◽  
Mark E. Schweitzer
Keyword(s):  
Bone Marrow ◽  
Mr Imaging ◽  
Foot And Ankle ◽  
Bone Marrow Signal ◽  
Marrow Signal

scholarly journals Incidence and Evaluation of Incidental Abnormal Bone Marrow Signal on Magnetic Resonance Imaging

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Gunjan L. Shah ◽  
Aaron S. Rosenberg ◽  
Jamie Jarboe ◽  
Andreas Klein ◽  
Furha Cossor
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Complete Blood Count ◽  
Medical Center ◽  
Resonance Imaging ◽  
Bone Marrow Signal ◽  
Abnormal Bone Marrow ◽  
Marrow Signal

Purpose. The increased use of magnetic resonance imaging (MRI) has resulted in reports of incidental abnormal bone marrow (BM) signal. Our goal was to determine the evaluation of an incidental abnormal BM signal on MRI and the prevalence of a subsequent oncologic diagnosis.Methods. We conducted a retrospective cohort study of patients over age 18 undergoing MRI between May 2005 and October 2010 at Tufts Medical Center (TMC) with follow-up through November 2013. The electronic medical record was queried to determine imaging site, reason for scan, evaluation following radiology report, and final diagnosis.Results. 49,678 MRIs were done with 110 patients meeting inclusion criteria. Twenty two percent underwent some evaluation, most commonly a complete blood count, serum protein electrophoresis, or bone scan. With median follow-up of 41 months, 6% of patients were diagnosed with malignancies including multiple myeloma, non-Hodgkins lymphoma, metastatic non-small cell lung cancer, and metastatic adenocarcinoma. One patient who had not undergone evaluation developed breast cancer 24 months after the MRI.Conclusions. Incidentally noted abnormal or heterogeneous bone marrow signal on MRI was not inconsequential and should prompt further evaluation.

Bone Marrow Signal Alteration in the Extremities

2011 ◽  
Vol 196 (5) ◽  
pp. W492-W510 ◽  
Author(s):  
Justin W. Kung ◽  
Corrie M. Yablon ◽  
Ronald L. Eisenberg
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Signal ◽  
Marrow Signal

Involvement of the proximal tibiofibular joint in ankylosing spondylitis

2009 ◽  
Vol 50 (4) ◽  
pp. 418-422 ◽  
Author(s):  
Hyun Pyo Hong ◽  
Hye Won Chung ◽  
Byeong-Kyoo Choi ◽  
Young Cheol Yoon ◽  
Sang Hee Choi
Keyword(s):  
Bone Marrow ◽  
Lumbar Spine ◽  
Ankylosing Spondylitis ◽  
Signal Intensity ◽  
Proximal Tibiofibular Joint ◽  
Plain Radiographs ◽  
Bone Marrow Signal ◽  
Abnormal Bone Marrow ◽  
Marrow Signal ◽  
Subchondral Sclerosis

Background: Ankylosing spondylitis (AS) may affect peripheral joints, with the shoulder, hip, and knee being well known involved sites. However, involvement of the proximal tibiofibular (PTF) joint has not yet been investigated. Purpose: To evaluate PTF joint abnormalities in patients with AS. Material and Methods: From July 1997 to June 2005, 16 patients (15 male, one female; mean age 25 years), who were clinically diagnosed with AS, underwent magnetic resonance imaging (MRI) to evaluate knee pain. All patients also underwent plain radiographs of the knee, lumbar spine, and pelvis. Twenty knee MRIs (bilateral in four patients) and 16 sets of knee, lumbar spine, and pelvic radiographs were retrospectively reviewed in order to evaluate possible AS involvement. The presence of abnormalities suggesting AS involvement were recorded separately in the sacroiliac joints, lumbar spine, hip, and femorotibial and PTF joints. If the PTF joint showed any pathologic findings, the radiologic findings were recorded. Results: Three of 16 patients (18.7%) had pathologic features of the PTF joint observed by plain radiographs or MRI. One of these three patients showed bilateral involvement of the PTF joints on plain radiographs, while the other two patients showed unilateral involvement on MRI. Subchondral sclerosis, cartilage abnormality, erosion, and abnormal bone marrow signal intensity were identified on MRI. Plain radiographs of two patients revealed subchondral sclerosis and spur formation in the PTF joint. The frequencies of involvement of other joints in the 16 patients were as follows: lumbar spine, n=5 (31%), hip joint, n=1 (6%) (identified by plain radiographs), and femorotibial joints, n=10 (62.5%) (identified by knee MRI). Conclusion: MR imaging of the PTF joint can depict synovial changes and their effect on joint structures in patients with AS. The MRI findings of AS involving the PTF joints are subchondral sclerosis, cartilage abnormality, erosion, and abnormal bone marrow signal intensity.

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