scholarly journals P1277EFFECT OF HEMODIALYSIS ON PERIPAPILLARY CHOROIDAL THICKNESS AND OPTIC NERVE HEAD PARAMETERS MEASURED BY SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Won June Lee ◽  
Yong Un Shin ◽  
Mincheol Seong

Abstract Background and Aims To investigate the effect of hemodialysis (HD) on peripapillary choroidal thickness (PCT) and optic nerve head (ONH) parameters by swept-source optical coherence (SS-OCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Method A prospective observational study was performed on 29 patients who underwent HD for ESKD. Detailed ophthalmologic examinations and SS-OCT were performed immediately before and after HD. The PCT were measured using the modification tool in the built-in OCT image viewer program. The ONH parameters including rim area (RA) and vertical cup-to-disc ratio (VCDR) were obtained using built-in software. Changes in PCT, and ONH parameters before and after HD were statistically analyzed. Results Average PCT significantly decreased from 127.3 ± 49.2 before HD to 117.1 ± 50.9 after HD (P<0.001). The RA increased and VCDR decreased significantly after HD (P=0.001 and P=0.027, respectively). Disc area did not show significant change after HD (P=0.648). Significant correlation was found between changes in PCT and changes in macular choroidal thickness (rho=0.547, P=0.002). Conclusion We observed significant decrease in PCT and significant changes in ONH parameters after HD. Our study suggest that HD can give influence on the ONH and its surrounding structure.

2019 ◽  
Vol 28 (3) ◽  
pp. 188-193 ◽  
Author(s):  
Joanne C. Wen ◽  
Chieh-Li Chen ◽  
Kasra A. Rezaei ◽  
Jennifer R. Chao ◽  
Atma Vemulakonda ◽  
...  

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Won June Lee ◽  
Rimkyung Hong ◽  
Min Ho Kang ◽  
Heeyoon Cho ◽  
Sang-Woong Han ◽  
...  

2019 ◽  
Vol 30 (4) ◽  
pp. 756-763 ◽  
Author(s):  
José Ignacio Fernández-Vigo ◽  
Bachar Kudsieh ◽  
Ana Macarro-Merino ◽  
Pedro Arriola-Villalobos ◽  
José María Martínez-de-la-Casa ◽  
...  

Purpose: To assess the reproducibility of swept-source optical coherence tomography angiography (SS-OCTA) for macular and optic nerve head (ONH) vessel density (VD). Methods: Cross-sectional study using the Triton OCTA (Topcon, Tokyo, Japan), for VD (%) measurements in 40 eyes of 40 healthy subjects on two 6 × 6 mm scans of the macula and ONH across five subfields (central, superior, inferior, temporal, and nasal) at different segmentation levels: superficial capillary plexus (SCP), deep capillary plexus (DCP), outer retina, and choriocapillaris. Reproducibility values were summarized as intraclass correlation coefficients (ICCs) and coefficients of variations (CV). Results: ICCs for the macular VD measurements in the central zone were 0.874, 0.770, 0.575, 0.718 at the levels SCP, DCP, outer retina, and choriocapillaris, respectively, while worse ICCs were obtained for the parafoveal subfields (ICC ⩽ 0.589); CVs were 2.8%–6.7%. The reproducibility of the ONH superficial VD was ICC = 0.941 for the papillary region and was ICC = 0.499–0.853 for the peripapillary zone; CVs ranged from 4.8% to 17%. Peripapillary VD showed an ICC = 0.533–0.770 in the DCP layer, and 0.572–0.828 in the choriocapillaris. Lowest VD were obtained for the macular SCP and DCP (23% and 22%, respectively), in the foveal zone, while greatest VD were recorded in the nasal and temporal peripapillary subfields at the level of the choriocapillaris (both 68%). Conclusions: The new SS-OCTA software served to quantify macular and ONH VD with a reproducibility that was good in the central zones (foveal and papillary, respectively) and moderate in the peripheral zones (parafoveal and peripapillary).


2017 ◽  
Vol 26 (9) ◽  
pp. 798-804 ◽  
Author(s):  
Edem Tsikata ◽  
Alice C. Vercellin Verticchio ◽  
Iryna Falkenstein ◽  
Linda Yi-Chieh Poon ◽  
Stacey Brauner ◽  
...  

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