Dose Proportionality of Licarbazepine Pharmacokinetics after Single and Repeated Oral Doses in Healthy Volunteers

2007 ◽  
Vol 21 (5) ◽  
Author(s):  
Claire Souppart ◽  
Michael Merz ◽  
Sebastien Balez ◽  
Anni Agarwal ◽  
Francois Mercier ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Dose Proportionality ◽  
Oral Doses

S-OXIDATION OF THIORIDAZINE TO PSYCHOACTIVE METABOLITES: AN ORAL DOSE-PROPORTIONALITY STUDY IN HEALTHY VOLUNTEERS

1988 ◽  
Vol 6 (3-4) ◽  
Author(s):  
B.S. Chakraborty ◽  
E.M. Hawes ◽  
G. McKay ◽  
J.W. Hubbard ◽  
E.D. Korchinski ◽  
...  
Keyword(s):  
Oral Dose ◽  
Healthy Volunteers ◽  
Dose Proportionality ◽  
S Oxidation

Clinical pharmacokinetics of procaterol: Dose proportionality after administration of single oral doses

1992 ◽  
Vol 13 (9) ◽  
pp. 663-669 ◽  
Author(s):  
Michael A. Eldon ◽  
Debbie S. Blake ◽  
Michael J. Coon ◽  
Gerald D. Nordblom ◽  
Allen J. Sedman ◽  
...  
Keyword(s):  
Dose Proportionality ◽  
Clinical Pharmacokinetics ◽  
Oral Doses

Pharmacokinetics and Dose Proportionality of Domperidone in Healthy Volunteers

1986 ◽  
Vol 26 (8) ◽  
pp. 628-632 ◽  
Author(s):  
Yih-Chain Huang ◽  
John L. Colaizzi ◽  
Robert H. Bierman ◽  
Robert Woestenborghs ◽  
Joseph J. P. Heykants
Keyword(s):  
Healthy Volunteers ◽  
Dose Proportionality

Tolerability of Increasing Single Oral Doses of Clentiazem in Healthy Volunteers

1992 ◽  
Vol 4 (3) ◽  
pp. 276-282 ◽  
Author(s):  
Jean-Marie Houle ◽  
Pierre Major ◽  
John McCans ◽  
Hélène Landriault ◽  
Marc LeFebvre ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Oral Doses

Inhibition of Platelet Aggregation in Man by Indobufen (K 3920)

1981 ◽  
Vol 9 (1) ◽  
pp. 12-17 ◽  
Author(s):  
A Vittoria ◽  
F Laghi Pasini ◽  
G L Messa ◽  
T Di Perri ◽  
G Corvi ◽  
...  
Keyword(s):  
Platelet Aggregation ◽  
Healthy Volunteers ◽  
Crossover Trial ◽  
Marked Effect ◽  
Threshold Concentration ◽  
Dose Effect ◽  
Inhibition Of Platelet Aggregation ◽  
Oral Doses

A complete crossover trial was undertaken in six healthy volunteers to gain information on dose-effect responses to indobufen by assessing the intensity and duration of the effect of 3 single oral doses of the drug on platelet aggregation induced by threshold concentration of ADP and by 3 added doses of collagen. The results of the study confirm that the activity is dose-related and is reversible since 24 hours after administration it has practically disappeared. The effect of the same dose of indobufen differed significantly according to the amount of collagen added to plasma, whereas increasing doses of indobufen provoked a significantly more marked effect when the amount of inducer employed was the same.

INVESTIGATION OF DOSE PROPORTIONALITY AND ABSOLUTE BIOAVAILABILITY OF BROFAROMINE IN HEALTHY VOLUNTEERS

1992 ◽  
Vol 15 ◽  
pp. 430B ◽  
Author(s):  
K. H. Antonin ◽  
K. Kucher ◽  
L. Fuchs ◽  
P. R. Bieck ◽  
E. Schmidt
Keyword(s):  
Healthy Volunteers ◽  
Dose Proportionality ◽  
Absolute Bioavailability

scholarly journals Suction-induced blister fluid penetration of cefdinir in healthy volunteers following ascending oral doses

1995 ◽  
Vol 39 (5) ◽  
pp. 1082-1086 ◽  
Author(s):  
M. Richer ◽  
S. Allard ◽  
L. Manseau ◽  
F. Vallee ◽  
R. Pak ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Blister Fluid ◽  
Fluid Penetration ◽  
Oral Doses
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