Dissociation between blood pressure reduction and fall in proteinuria in primary renal disease: a randomized double-blind trial

2002 ◽  
Vol 20 (4) ◽  
pp. 729-737 ◽  
1964 ◽  
Vol 2 (14) ◽  
pp. 55-56

Hydromet (MSD) is a mixture of 250 mg methyldopa with 15 mg hydrochlorothiazide in a tablet offered for the treatment of hypertension. Both drugs may lower the blood pressure when it is raised. In a double-blind trial1 a combination of the two (given in separate tablets) was found to be better than either drug alone combined with a placebo. The dose of hydrochlorothiazide was 100 mg daily and the dose of methyldopa was increased from 1 to 2 G daily after the first week.


BMJ ◽  
2010 ◽  
Vol 340 (mar25 3) ◽  
pp. c1197-c1197 ◽  
Author(s):  
G. Mancia ◽  
G. Parati ◽  
M. Revera ◽  
G. Bilo ◽  
A. Giuliano ◽  
...  

1987 ◽  
Vol 76 (03) ◽  
pp. 114-119 ◽  
Author(s):  
M. Bignamini ◽  
A. Bertoli ◽  
A.M. Consolandi ◽  
N. Dovera ◽  
M. Saruggia ◽  
...  

AbstractTaking into account the toxicology of soluble barium salts, the authors treated 32 hypertensive subjects who were confirned to bed in two old people's homes with Baryta carbonica 15 CH versus placebo in a randomized double-blind study. Seventeen patients were given Baryta carbonica and 15 placebo. Taking the groups as a whole, no statistically significant differences were found between the effects of placebo and active drug on the blood pressure. But the four subjects who had been prospectively considered sensitive and were treated with Baryta carbonica gave strongly positive results. Some interesting conclusions were arrived at both from the general medical and the homœopathic point of view.


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