Efficacy and Safety of a Once-Daily Fixed-Dose Combination of Abacavir/Lamivudine Compared With Abacavir Twice Daily and Lamivudine Once Daily as Separate Entities in Antiretroviral-Experienced HIV-1-Infected Patients (CAL30001 Study)

2006 ◽  
Vol 41 (5) ◽  
pp. 598-606 ◽  
Author(s):  
Anthony LaMarca ◽  
Nathan Clumeck ◽  
Andreas Plettenberg ◽  
Pere Domingo ◽  
Kaisong Fu ◽  
...  
Keyword(s):  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Efficacy And Safety ◽  
Once Daily ◽  
Dose Combination ◽  
Hiv 1

scholarly journals Evaluation of Efficacy and Safety of Oral Olmesartan+ Chlorthalidone Combination in the Management of Hypertension in Indian Patients

2017 ◽  
Vol 18 (1) ◽  
pp. 6-9
Author(s):  
Ashok Khanna ◽  
AA Faruqui
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Fixed Dose Combination ◽  
Rural Populations ◽  
Fixed Dose ◽  
Efficacy And Safety ◽  
Once Daily ◽  
All Cause Mortality ◽  
Dose Combination

Hypertension is the most prevalent chronic disease in India and its prevalence is rapidly increasing among urban and rural populations. Reducing blood pressure can decrease cardiovascular risk and all cause mortality. This study was conducted to assess the efficacy and safety of fixed dose combination of Olmesartan 40 mg and Chlorthalidone12.5mg. 30 hypertensive patients having systolic blood pressure ? 160 mmHg and diastolic blood pressure ?100 mmHg who were uncontrolled on monotherapy with olmesartan were enrolled in this study. The treatment period was of 60 days and patients were administered once daily fixed dose combination of Olmesartan40 mg and Chlorthalidone 12.5 mg. Patients were evaluated on 15th, 30th and 60th days of treatment.There was statistically significant (p<0.0001) decrease in systolic blood pressure from baseline to 15th, 30th and 60thday of treatmentmean±SD (179.1±13.38 mmHg vs. 169.3±13.05, 154.3±13.31, and 142.7±6.91mmHg) respectively. Similarly the diastolic blood pressure (DBP) was significantly (p<0.0001) reduced from the baseline to the 15th, 30th and 60thday of treatment (94.97±5.75mmHg vs.86.67±4.79, 80.33±1.82 and 76.7±4.32 mmHg respectively). Thus fixed dose combination of Olmesartan and Chlorthalidonewas found to be effective and safe option for the optimal management of hypertension.J MEDICINE January 2017; 18 (1) : 6-9

Efficacy and safety of aclidinium/formoterol fixed-dose combination in patients with COPD, stratified by ICS use

Pneumologie ◽  
2016 ◽  
Vol 70 (S 01) ◽  
Author(s):  
ED Bateman ◽  
K Chapman ◽  
S Rennard ◽  
L Rekeda ◽  
M Moya ◽  
...  
Keyword(s):  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Efficacy And Safety ◽  
Dose Combination

Prevalence and risk factors for developing K65R mutations among HIV-1 infected patients who fail an initial regimen of fixed-dose combination of stavudine, lamivudine, and nevirapine

2008 ◽  
Vol 41 (4) ◽  
pp. 310-313 ◽  
Author(s):  
Somnuek Sungkanuparph ◽  
Weerawat Manosuthi ◽  
Sasisopin Kiertiburanakul ◽  
Nipa Saekang ◽  
Wantanit Pairoj ◽  
...  
Keyword(s):  
Risk Factors ◽  
Fixed Dose Combination ◽  
Fixed Dose ◽  
Initial Regimen ◽  
Dose Combination ◽  
Hiv 1
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