Randomized Comparison of Packed Red Blood Cell-to-Fresh Frozen Plasma Transfusion Ratio of 4

2017 ◽  
Vol 38 (3) ◽  
pp. 194-201 ◽  
Author(s):  
Laura A. Galganski ◽  
David G. Greenhalgh ◽  
Soman Sen ◽  
Tina L. Palmieri
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Fresh Frozen Plasma ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Transfusion Ratio ◽  
Frozen Plasma

scholarly journals Examining 1:1 vs. 4:1 Packed Red Blood Cell to Fresh Frozen Plasma Ratio Transfusion During Pediatric Burn Excision

2020 ◽  
Vol 41 (3) ◽  
pp. 443-449 ◽  
Author(s):  
Shawn Tejiram ◽  
Soman Sen ◽  
Kathleen S Romanowski ◽  
David G Greenhalgh ◽  
Tina L Palmieri
Keyword(s):  
Blood Cell ◽  
Body Surface ◽  
Red Blood Cell ◽  
Total Body Surface Area ◽  
Blood Stream ◽  
Fresh Frozen Plasma ◽  
Plasma Transfusion ◽  
Fresh Frozen ◽  
Total Body ◽  
Frozen Plasma

Abstract Blood transfusions following major burn injury are common due to operative losses, blood sampling, and burn physiology. While massive transfusion improves outcomes in adult trauma patients, literature examining its effect in critically ill children is limited. The study purpose was to prospectively compare outcomes of major pediatric burns receiving a 1:1 vs. 4:1 packed red blood cell to fresh frozen plasma transfusion strategy during massive burn excision. Children with >20% total body surface area burns were randomized to a 1:1 or 4:1 packed red blood cell/fresh frozen plasma transfusion ratio during burn excision. Parameters examined include patient demographics, burn size, pediatric risk of mortality (PRISM) scores, pediatric logistic organ dysfunction scores, laboratory values, total blood products transfused, and the presence of blood stream infections or pneumonia. A total of 68 children who met inclusion criteria were randomized into two groups (n = 34). Mean age, PRISM scores, estimated blood loss (600 ml (400–1175 ml) vs. 600 ml (300–1150 ml), P = 0.68), ventilator days (5 vs. 9, P = 0.47), and length of stay (57 vs. 60 days, P = 0.24) had no difference. No differences in frequency of blood stream infection (20 vs. 18, P = 0.46) or pneumonia events (68 vs. 116, P = 0.08) were noted. On multivariate analysis, only total body surface area burn size, inhalation injury, and PRISM scores (P < 0.05) were significantly associated with infections.

Relationship between fresh frozen plasma to packed red blood cell transfusion ratio and mortality in cardiovascular surgery

2018 ◽  
Vol 32 (4) ◽  
pp. 539-546
Author(s):  
Akito Tsukinaga ◽  
Takuma Maeda ◽  
Shunsuke Takaki ◽  
Nobuaki Michihata ◽  
Yoshihiko Ohnishi ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cardiovascular Surgery ◽  
Fresh Frozen Plasma ◽  
Red Blood Cell Transfusion ◽  
Fresh Frozen ◽  
Transfusion Ratio ◽  
Frozen Plasma

scholarly journals Red blood cell transfusion is associated with further bleeding and fresh-frozen plasma with mortality in nonvariceal upper gastrointestinal bleeding

Transfusion ◽  
2015 ◽  
Vol 56 (4) ◽  
pp. 816-826 ◽  
Author(s):  
Kavitha Subramaniam ◽  
Katrina Spilsbury ◽  
Oyekoya T. Ayonrinde ◽  
Faye Latchmiah ◽  
Syed A. Mukhtar ◽  
...  
Keyword(s):  
Blood Cell ◽  
Gastrointestinal Bleeding ◽  
Red Blood Cell ◽  
Upper Gastrointestinal Bleeding ◽  
Fresh Frozen Plasma ◽  
Red Blood Cell Transfusion ◽  
Fresh Frozen ◽  
Upper Gastrointestinal ◽  
Frozen Plasma

203. The Influence of Hemoglobine Levels, Red Blood Cell and Fresh Frozen Plasma Use on Postoperative Deposition and Outcome

2009 ◽  
Vol 9 (10) ◽  
pp. 107S-108S
Author(s):  
Albert Pull Ter Gunne ◽  
Richard Skolasky ◽  
Hillary Ross ◽  
David Cohen
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Fresh Frozen Plasma ◽  
Fresh Frozen ◽  
Frozen Plasma
Sign in / Sign up

Export Citation Format

Share Document