Introduction. Intussusception is a rare phenomenon in adults. It is caused
mainly by malignant neoplasm. Primary lymphoma of the colon is a rare
malignancy of the large intestine. The association of intussusception in
adult and primary colorectal lymphoma is a diagnostic challenge, since they
occur with a variety of atypical symptoms. Case Outline. We report a case of
ileocolic intussusception in a 26-year-old man induced by primary lymphoma of
the cecum. He was admitted to our hospital for incomplete intestinal
obstruction. After thorough diagnostic work-up (plain abdominal radiography,
abdominal ultrasonography, multi-slice computerized tomography, colonoscopy
with biopsy), the patient underwent surgery. Intraoperative findings
confirmed lymphoma as the cause of intussusception. The right hemicolectomy
was carried out with end-to-side ileo-transverse anastomosis. Conclusion.
Primary colorectal lymphomas should be considered in differential diagnosis
of intussusceptions in adults. The treatment of choice is a radical resection
where all oncological standards must be fulfilled.