ENDODIATHERMY PLUS PHOTOCOAGULATION AS TREATMENT OF SCLEROTOMY SITE VASCULARIZATION SECONDARY TO PARS PLANA VITRECTOMY FOR PROLIFERATIVE DIABETIC RETINOPATHY

We evaluated the effect of intravitreal bevacizumab (IVB) injection before pars plana vitrectomy (PPV) on intravitreal hemorrhage (VH) during and after vitrectomy for postoperative the first day and the first month in pseudophakic patients with proliferative diabetic retinopathy (PDR). This retrospective study was performed on 44 eyes of 44 patients who underwent vitrectomy for PDR. Patients were divided into PPV (n = 22 eyes) and PPV + IVB (n = 22 eyes) groups. Injection of bevacizumab (1.25 mg/0.05 mL) was performed 3 days before vitrectomy. Outcomes of visual acuity as well as intraoperative and postoperative VH were compared between the two groups. One month after surgery, visual acuity improved in PPV and PPV + IVB groups ( P = 0.005, P = 0.006), respectively. There was no difference between the two groups in best corrected visual acuity at baseline and after vitrectomy ( P = 0.71). Intraoperative bleeding into the vitreous was recorded in 14 (63.6%) cases in the PPV group and in 7 (31.8%) cases in the PPV + IVB group. The first month, intravitreal hemorrhage was recorded in six patients in the PPV group and in two patients in the PPV + IVB group ( P = 0.03). The mean pre-postoperative central macular thickness was similar in both groups. Intravitreal injection of IVB before vitrectomy decreased the rate of VH at the time of surgery and at the first postoperative month in patients with PDR.

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OCULAR FINDINGS AT INITIAL PAN RETINAL PHOTOCOAGULATION FOR PROLIFERATIVE DIABETIC RETINOPATHY PREDICT THE NEED FOR FUTURE PARS PLANA VITRECTOMY

Retina ◽

10.1097/iae.0000000000000192 ◽

2014 ◽

Vol 34 (10) ◽

pp. 1997-2002 ◽

Cited By ~ 4

Author(s):

Ravi Parikh ◽

Rohan J. Shah ◽

Jacob P. VanHouten ◽

Edward F. Cherney

Keyword(s):

Diabetic Retinopathy ◽

Proliferative Diabetic Retinopathy ◽

Pars Plana Vitrectomy ◽

Ocular Findings ◽

Pan Retinal Photocoagulation ◽

Pars Plana ◽

Retinal Photocoagulation

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Intraoperative optical coherence tomography and proportional reflux hydrodissection-guided pars plana vitrectomy for complex severe proliferative diabetic retinopathy

Indian Journal of Ophthalmology ◽

10.4103/ijo.ijo_978_19 ◽

2020 ◽

Vol 68 (1) ◽

pp. 177 ◽

Cited By ~ 2

Author(s):

Vishali Gupta ◽

Aniruddha Agarwal

Keyword(s):

Optical Coherence Tomography ◽

Diabetic Retinopathy ◽

Proliferative Diabetic Retinopathy ◽

Pars Plana Vitrectomy ◽

Optical Coherence ◽

Intraoperative Optical Coherence Tomography ◽

Pars Plana

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Does Pars Plana Vitrectomy Improve Visual Outcomes in Patients with Complications of Proliferative Diabetic Retinopathy

50 Studies Every Ophthalmologist Should Know ◽

10.1093/med/9780190050726.003.0031 ◽

2020 ◽

pp. 185-190

Author(s):

Alan D. Penman ◽

Kimberly W. Crowder ◽

William M. Watkins

Keyword(s):

Clinical Trial ◽

Diabetic Retinopathy ◽

Retinal Detachment ◽

Proliferative Diabetic Retinopathy ◽

Pars Plana Vitrectomy ◽

Vitreous Hemorrhage ◽

Diabetic Patients ◽

Visual Outcomes ◽

Management Of Complications ◽

Pars Plana

The Early Treatment Diabetic Retinopathy Study (ETDRS) was a randomized clinical trial involving nearly four thousand diabetic patients with early proliferative retinopathy, moderate to severe nonproliferative retinopathy, and/or diabetic macular edema in each eye. This paper (ETDRS report number 17) describes the baseline previtrectomy characteristics, initial treatment assignments, indications for vitrectomy, and visual outcomes in the subgroup of patients in the ETDRS who had pars plana vitrectomy (PPV). The study showed that pars plana vitrectomy could improve visual outcomes in patients with complications from proliferative diabetic retinopathy such as vitreous hemorrhage and retinal detachment. PPV continues to play an important role in the management of complications from proliferative diabetic retinopathy.

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