Pancreatic Sampling by Endoscopic Ultrasound–Guided Fine-Needle Aspiration and Needle Biopsy From the Cytopathology Perspective

2015 ◽  
Vol 20 (4) ◽  
pp. 147-155
Author(s):  
Jessica B. Dwyer ◽  
Liron Pantanowitz ◽  
Sara E. Monaco
2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Lachlan R. Ayres ◽  
Elizabeth K. Kmiotek ◽  
Eric Lam ◽  
Jennifer J. Telford

Background and Aims. Endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) is the method of choice for sampling pancreatic lesions. This study compares the diagnostic accuracy and safety of FNB using a novel core needle to FNA in solid pancreatic lesions. Methods. A retrospective review of patients in whom EUS FNA or FNB was performed for solid pancreatic lesions was conducted. Diagnostic performance was calculated based upon a dual classification system: classification 1, only malignant pathology considered a true positive, versus classification 2, atypical, suspicious, and malignant pathology considered a true positive. Results. 43 patients underwent FNB compared with 51 FNA. Using classification 1, sensitivity was 74.0% versus 80.0%, specificity 100% versus 100%, and diagnostic accuracy 77.0% versus 80.0% for FNB versus FNA, respectively (all p>0.05). Using classification 2, sensitivity was 97% versus 94.0%, specificity 100% versus 100%, and diagnostic accuracy 98.0% versus 94.0% for FNB versus FNA, respectively (all p>0.05). FNB required significantly fewer needle passes (median = 2) compared to FNA (median = 3; p<0.001). Adverse events occurred in two (4.5%) FNB patients compared with none in the FNA group (p>0.05). Conclusion. FNA and FNB have comparable sensitivity and diagnostic accuracy. FNB required fewer passes.


2015 ◽  
Vol 34 (12) ◽  
pp. 2163-2169 ◽  
Author(s):  
Young Keun Sur ◽  
Young Chul Kim ◽  
Jai Keun Kim ◽  
Jei Hee Lee ◽  
Byung Moo Yoo ◽  
...  

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