scholarly journals Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay

1993 ◽  
Vol 74 (6) ◽  
pp. 1093-1102 ◽  
Author(s):  
L. Stuyver ◽  
R. Rossau ◽  
A. Wyseur ◽  
M. Duhamel ◽  
B. Vanderborght ◽  
...  
1998 ◽  
Vol 36 (5) ◽  
pp. 1461-1463 ◽  
Author(s):  
S. Le Pogam ◽  
F. Dubois ◽  
R. Christen ◽  
C. Raby ◽  
A. Cavicchini ◽  
...  

Two methods for genotyping hepatitis C virus (DNA enzyme immunoassay [DEIA] and line probe assay [Inno-LiPA HCV I and II]) were compared on 120 samples and of these 87% were assigned to the same subtype by both assays. There were 15 subtyping discrepancies which involved 5% of type 1 isolates and 90% of type 2 isolates. Amplified products from the core and 5′ untranslated regions (UTR) were sequenced to resolve conflicts. Type 1 discordant samples had a guanosine at position −99 in the 5′ UTR, a characteristic of genotype 1b, and a core region typical of subtype 1a. The eight isolates classified as 2a/2c by LiPA and as subtype 2c by DEIA belonged to type 2.


Gene ◽  
1991 ◽  
Vol 103 (2) ◽  
pp. 163-169 ◽  
Author(s):  
Klaus Fuchs ◽  
Manfred Motz ◽  
Eckart Schreier ◽  
Reinhart Zachoval ◽  
Friedrich Deinhardt ◽  
...  

1994 ◽  
Vol 21 (1) ◽  
pp. 122-129 ◽  
Author(s):  
Leen-Jan van Doorn ◽  
Bernhard Kleter ◽  
Lieven Stuyver ◽  
Geert Maertens ◽  
Hans Brouwer ◽  
...  

1996 ◽  
Vol 34 (9) ◽  
pp. 2259-2266 ◽  
Author(s):  
L Stuyver ◽  
A Wyseur ◽  
W van Arnhem ◽  
F Hernandez ◽  
G Maertens

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