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(FIVE YEARS 20442)



Xiaoni Wei

With the rapidly developing of the scientific research in the field of sports, big data analytics and information science are used to carry out technical and tactical statistical analysis of competition or training videos. The table tennis is a skill oriented sport. The technique and tactics in table tennis are the core factors to win the game. With the endlessly emerging innovative playing techniques and tactics, the players have their own competition styles. According to the competition events among athletes, the athletes’ competition relationship network is constructed and the players’ ranking is established. The ranking can be used to help table tennis players improve daily training and understand their ability. In this paper, the table tennis players’ ranking is established their competition videos and their prestige scores in the table tennis players’ competition relationship network.

Camila P. Cagna ◽  
Osvaldo Guedes Filho ◽  
Alexandre R. C. Silva ◽  
Cássio A. Tormena

ABSTRACT The objective of this study was to automate the acquisition of water travel time, as well as the computation of hydraulic conductivity of saturated soil by the falling head method, using water sensors and the Arduino platform. To automate the measurement of travel time, the Arduino Uno board was used, and two water sensors were installed at the initial (h0) and final (h1) heights of the water inside the core. When the water flows across the soil and the water level passes the bottom part of the initial sensor (h0), the time recording starts; it ends when the water is absent from the final height of the second sensor (h1). The equation for calculating the hydraulic conductivity was inserted into the algorithm so the calculation was automatic. Undisturbed soil samples were taken in a long-term no-tillage area. There were no significant differences for the time and hydraulic conductivity means between the permeameters. The coefficient of the residual mass index showed an overestimation of the time variable; thus, the automated permeameter improves the precision of time recording and saturated hydraulic conductivity estimated by the falling head method.

2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Herolinda Murati-Leka ◽  
Besnik Fetai

Purpose The purpose of this paper will be on finding and analyzing the impact of government on the information and communication technology (ICT) companies’ innovation performance. The study aims to conduct in-depth research about the government as an integrated actor of the innovation ecosystem (IE), not a sole member. This would be the core finding toward doing further research about the impact of the innovation ecosystem in the ICT sector in Kosovo. Design/methodology/approach Quantitative research has been considered the most suitable data collection method. Furthermore, in this study, it is used convenience sampling as a technique of the sampling process. The sample size of this study is 106 participants. The participants are owners or representatives of ICT companies in Kosovo. Since the study is conducted using the deductive approach, the questionnaire is considered to be the most suitable instrument for gathering data. Findings This paper provides empirical insights that the company’s size and the dedicated department for research and development have no impact on how the company takes advantage of public funding from the government. Furthermore, the authors of the paper found out that government has a positive impact on companies’ introduction of new products and services, while the impact of the government on a company’s financial performance was insignificant. Research limitations/implications The future research direction should be firstly on studying other IE actors and their impact on companies’ innovation performance and secondly on measuring the IE actors as a set of actors to have a broader picture on how IE impacts the companies’ innovation performance. Practical implications The scientific contribution of this study will be on mapping, analyzing and proposing government policies in accordance with the findings of this study that would lead to a more comprehensive and sustainable IE in Kosovo. Originality/value This study tries to fulfill an identified need to study the impact of interconnected actors of an innovation ecosystem and to show how they affect each other. In this study, it is taken for research one fragment of a set of actors.

2022 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Luis Diego Soto Kiewit ◽  
Bianca Vienni Baptista

Purpose This paper aims to analyse innovation models and interdisciplinarity in science, technology and innovation (STI) policy in Costa Rica between 2015 and 2021. The core focus is to evaluate the public policy in light of the groundwork that sustains the designed and proposed actions. Design/methodology/approach The authors applied a qualitative approach to build a set of dimensions and conducted content-analysis of selected documents. The analysis encompasses all current STI public policy documents in Costa Rica, including the planning instruments of the Central Government and the National Policy on STI. Findings The main findings show that STI policy in Costa Rica is based on different innovation models, but the projects and instruments themselves show the predominance of the reductionist model. Innovation receives a residual role. In turn, interdisciplinarity is based on the concept of convergence, which limits disciplinary collaboration to the natural, physical and engineering sciences, minimising contributions from other fields of knowledge to an instrumental role in innovation processes. Practical implications The authors conclude that the interlinkage between open innovation models, the participation of diverse societal actors and the inclusion of an interdisciplinary perspective leads to inclusive and more democratic public policy, allowing more sectors and organisations to benefit from innovation processes. This would imply a greater reach and impact of the policy, conditions that translate into innovation achievements and a better return on public investment. Originality/value This paper contributes to current discussions on STI policy by studying the implications of the link among policies, innovation models and interdisciplinarity.

2022 ◽  
Vol 6 ◽  
Nidaa Hussain Fahmi Al-Khazraji

This paper studies the core-identity of Al Mustafa (the chosen) in Gibran's book The Prophet (1923) as an individual property by investigating its discursive features as revealed in the words and deeds of the participants in the discourse. The study deals with how Gibran refers to the protagonist and how this portrayal reflects on the identity of the writer. It examines how the prophet refers to himself, his worries and needs, how the interlocutors address him in the discourse and finally how the telling of the on-going actions leads to the perception of Al-Mustafa as a prophetic figure. The results show that the source of the power of such a discursive identity is neither nature, nor certain established institutions, but the people of Orphalese themselves (the participants in the discourse), plus those readers of Gibran's book who discern a prophetic figure in his words. The process through which this power works is that of “recognition”, in that rational individuals recognise Al-Mustafa as a Prophet in the discourse. Such recognition is realised as an active “self-achievement” arising as a deserved property of the ways in which the prophet's words and deeds are recognised by his followers.

2022 ◽  
Vol 90 (3) ◽  
Gregor J. Gassner ◽  
Magnus Svärd ◽  
Florian J. Hindenlang

AbstractThe focus of the present research is on the analysis of local energy stability of high-order (including split-form) summation-by-parts methods, with e.g. two-point entropy-conserving fluxes, approximating non-linear conservation laws. Our main finding is that local energy stability, i.e., the numerical growth rate does not exceed the growth rate of the continuous problem, is not guaranteed even when the scheme is non-linearly stable and that this may have adverse implications for simulation results. We show that entropy-conserving two-point fluxes are inherently locally energy unstable, as they can be dissipative or anti-dissipative. Unfortunately, these fluxes are at the core of many commonly used high-order entropy-stable extensions, including split-form summation-by-parts discontinuous Galerkin spectral element methods (or spectral collocation methods). For the non-linear Burgers equation, we further demonstrate numerically that such schemes cause exponential growth of errors during the simulation. Furthermore, we encounter a similar abnormal behaviour for the compressible Euler equations, for a smooth exact solution of a density wave. Finally, for the same case, we demonstrate numerically that other commonly known split-forms, such as the Kennedy and Gruber splitting, are also locally energy unstable.

2022 ◽  
Vol 22 (1) ◽  
Nabamita Boruah ◽  
Chongtham Sovachandra Singh ◽  
Pooja Swargiary ◽  
Hughbert Dkhar ◽  
Anupam Chatterjee

Abstract Background Raw areca nut (RAN) consumption induces oral, esophageal and gastric cancers, which are significantly associated with the overexpression of pituitary tumor transforming gene 1/securin and chromosomal instability (CIN). An association of Securin/PTTG1 upregulation and gastric cancer in human was also demonstrated earlier. Since the molecular mechanism underlying securin upregulation remains unclear, this study intended to investigate the association of securin upregulation with the Rb-E2F1 circuit and epigenetic histone (H3) modification patterns both globally and in the promoter region of the securin gene. Methods Six groups of mice were used, and in the treated group, each mouse consumed 1 mg of RAN extract with lime per day ad libitum in the drinking water for 60 days, after which the dose was increased by 1 mg every 60 days. Histopathological evaluation of stomach tissues was performed and securin expression was analysed by immunoblotting as well as by immunohistochemistry. ChIP-qPCR assays were performed to evaluate the recruitment of different histone modifications in the core promoter region of securin gene as well as its upstream and downstream regions. Results All mice developed gastric cancer with securin overexpression after 300 days of feeding. Immunohistochemistry data revealed hyperphosphorylation of Rb and upregulation of E2F1 in the RAN-treated samples. Increased trimethylation of H3 lysine 4 and acetylation of H3 lysine 9 and 18 both globally and in the promoter region of the securin gene were observed by increasing the levels of lysine-N-methyltransferase 2A, lysine-acetyltransferase, EP-300 and PCAF after RAN treatment. ChIP-qPCR data revealed that the quantity of DNA fragments retrieved from the immunoprecipitated samples was maximum in the -83 to -192 region than further upstream and the downstream of the promoter for H3K4Me3, H3K9ac, H3K18ac and H3K9me3. Conclusions RAN-mediated pRb-inactivation induced securin upregulation, a putative E2F1 target, by inducing misregulation in chromatin remodeling in its promoter region, which led to transcriptional activation and subsequent development of chromosomal instability. Therefore, present results have led to the hypothesis that RAN-induced changes in the epigenetic landscape, securin overexpression and subsequent elevation of chromosomal instability is probably byproducts of inactivation of the pRb pathway.

Udo Kannengiesser ◽  
John S. Gero

AbstractThis paper investigates how the core technical processes of the INCOSE model of systems engineering differ from other models of designing used in the domains of mechanical engineering, software engineering and service design. The study is based on fine-grained datasets produced using mappings of the different models onto the function-behaviour-structure (FBS) ontology. By representing every model uniformly, the same statistical analyses can be carried out independently of the domain of the model. Results of correspondence analysis, cumulative occurrence analysis and Markov model analysis show that the INCOSE model differs from the other models in its increased emphasis on requirements and on behaviours derived from structure, in the uniqueness of its verification and validation phases, and in some patterns related to the temporal development and frequency distributions of FBS design issues.

BMC Genomics ◽  
2022 ◽  
Vol 23 (1) ◽  
Biplabendu Das ◽  
Charissa de Bekker

Abstract Background Circadian clocks allow organisms to anticipate daily fluctuations in their environment by driving rhythms in physiology and behavior. Inter-organismal differences in daily rhythms, called chronotypes, exist and can shift with age. In ants, age, caste-related behavior and chronotype appear to be linked. Brood-tending nurse ants are usually younger individuals and show “around-the-clock” activity. With age or in the absence of brood, nurses transition into foraging ants that show daily rhythms in activity. Ants can adaptively shift between these behavioral castes and caste-associated chronotypes depending on social context. We investigated how changes in daily gene expression could be contributing to such behavioral plasticity in Camponotus floridanus carpenter ants by combining time-course behavioral assays and RNA-Sequencing of forager and nurse brains. Results We found that nurse brains have three times fewer 24 h oscillating genes than foragers. However, several hundred genes that oscillated every 24 h in forager brains showed robust 8 h oscillations in nurses, including the core clock genes Period and Shaggy. These differentially rhythmic genes consisted of several components of the circadian entrainment and output pathway, including genes said to be involved in regulating insect locomotory behavior. We also found that Vitellogenin, known to regulate division of labor in social insects, showed robust 24 h oscillations in nurse brains but not in foragers. Finally, we found significant overlap between genes differentially expressed between the two ant castes and genes that show ultradian rhythms in daily expression. Conclusion This study provides a first look at the chronobiological differences in gene expression between forager and nurse ant brains. This endeavor allowed us to identify a putative molecular mechanism underlying plastic timekeeping: several components of the ant circadian clock and its output can seemingly oscillate at different harmonics of the circadian rhythm. We propose that such chronobiological plasticity has evolved to allow for distinct regulatory networks that underlie behavioral castes, while supporting swift caste transitions in response to colony demands. Behavioral division of labor is common among social insects. The links between chronobiological and behavioral plasticity that we found in C. floridanus, thus, likely represent a more general phenomenon that warrants further investigation.

2022 ◽  
Vol 27 (1) ◽  
Hongjuan You ◽  
Qi Li ◽  
Delong Kong ◽  
Xiangye Liu ◽  
Fanyun Kong ◽  

AbstractCanonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signaling are still not fully elucidated. Lysine acetylation is a significant protein modification which facilitates reversible regulation of the target protein function dependent on the activity of lysine acetyltransferases (KATs) and the catalytic function of lysine deacetylases (KDACs). Protein lysine acetylation has been classified into histone acetylation and non-histone protein acetylation. Histone acetylation is a kind of epigenetic modification, and it can modulate the transcription of important biological molecules in Wnt/β-catenin signaling. Additionally, as a type of post-translational modification, non-histone acetylation directly alters the function of the core molecules in Wnt/β-catenin signaling. Conversely, this signaling can regulate the expression and function of target molecules based on histone or non-histone protein acetylation. To date, various inhibitors targeting KATs and KDACs have been discovered, and some of these inhibitors exert their anti-tumor activity via blocking Wnt/β-catenin signaling. Here, we discuss the available evidence in understanding the complicated interaction of protein lysine acetylation with Wnt/β-catenin signaling, and lysine acetylation as a new target for cancer therapy via controlling this signaling.

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