Comparison of DNA Enzyme Immunoassay and Line Probe Assays (Inno-LiPA HCV I and II) for Hepatitis C Virus Genotyping
1998 ◽
Vol 36
(5)
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pp. 1461-1463
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Keyword(s):
The Core
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Two methods for genotyping hepatitis C virus (DNA enzyme immunoassay [DEIA] and line probe assay [Inno-LiPA HCV I and II]) were compared on 120 samples and of these 87% were assigned to the same subtype by both assays. There were 15 subtyping discrepancies which involved 5% of type 1 isolates and 90% of type 2 isolates. Amplified products from the core and 5′ untranslated regions (UTR) were sequenced to resolve conflicts. Type 1 discordant samples had a guanosine at position −99 in the 5′ UTR, a characteristic of genotype 1b, and a core region typical of subtype 1a. The eight isolates classified as 2a/2c by LiPA and as subtype 2c by DEIA belonged to type 2.
Keyword(s):
1994 ◽
Vol 48
(1)
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pp. 81-91
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Keyword(s):
Analysis of hepatitis C virus genotypes by a line probe assay and correlation with antibody profiles
1994 ◽
Vol 21
(1)
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pp. 122-129
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Keyword(s):
1999 ◽
Vol 6
(2)
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pp. 279-281
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